To the Editor,We acknowledge that the study in your journal titled, "Cardiac surgery in patients with atrial isomerism: Long-term results and outcomes" by Diego B. Ortega-Zhindón et al. is brilliantly written and we agree with the conclusion that patients with atrial isomerism (AI) must undergo a rigorous evaluation to determine an adequate repair strategy, considering univentricular RAI with a high possibility of morbidity and mortality.