Cardiac surgery-associated acute kidney injury: risk factors analysis and comparison of prediction models

Abstract

The performance of known prediction models for AKI-D was found reasonably well in the prediction of KDIGO-AKI, with the model by Thakar having the highest predictive value in the discrimination of patients with risk for all KDIGO-AKI stages.

Risk assessment of acute kidney injury following cardiopulmonary bypass

“…The incidence of RRT was 10%, which is within the range reported by Kiers et al (9.3%) [11]. Kristovic noted an incidence of 3.5% in a retrospective study, which is much lower than the values assessed in the present study [12]. Finally, from 31,677 patients who underwent open-heart surgery, 555 (1.7%) patients developed severe AKI requiring dialysis [13].…”

Correlation of cardiopulmonary bypass duration with acute renal failure after cardiac surgery

“…6 This imposes a considerable economic burden on the health care system. Prior studies have demonstrated prolonged duration of CPB as a risk factor for ARF 3,7,8,[10][11][12] ; however, CPB time is frequently dichotomized at heterogeneous time points.…”

Effect of perioperative statin therapy on renal outcome in patients undergoing cardiac surgery

“…Higher preoperative sCr was considered as an independent risk factor for postoperative AKI. [36] The studies of Christenson, [33] Prowle et al [18] and Billings et al [21] did not exclude patients with preoperative renal dysfunction which was diagnosed by elevated sCr and these 3 studies showed no protective effect of PST on renal outcome. Billings et al [21] even found that PST was associated with increased sCr on postoperative day 2 and AKI occurred in more patients with preoperative chronic kidney disease(CKD) randomized to atorvastatin than placebo.…”