Cardiac Sarcoidosis: A National Analysis of Arrhythmias, Conduction Blocks, and Icd's

Abstract

It is estimated that 20-25% of sarcoidosis patients with pulmonary/systemic involvement, have asymptomatic cardiac involvement. When signs or symptoms do occur, manifestations include conduction abnormalities, ventricular arrhythmias or sudden cardiac death. We sought to determine the prevalence of conduction abnormalities, arrhythmias and implantable cardiac defibrillators (ICD) in cardiac sarcoidosis (CS) along with comorbidities throughout the United States. METHODS:We conducted a retrospective analysis using the National Inpatient Sample (NIS-HCUP) database for all CS admissions in 2016 via the International Classification of Diseases 10 code D86.85. Codes used for arrhythmias and conduction delays included: AV block, fascicular blocks, bundle branch blocks (BBB) supraventricular tachycardia (SVT), atrial fibrillation (AF), atrial flutter (AFlut), premature ventricular contraction (PVC), SA-Node dysfunction and cardiac arrest (CA). Procedure codes for ICD placement during hospitalization used were: 02HK3KZ,

Inpatient characteristics, complications, and outcomes of patients with cardiac sarcoidosis: A study from the National Inpatient Sample

“…Sarcoid granulomas in ventricular myocardium can become foci for abnormal automaticity often leading to ventricular arrhythmias. 3 , 4 , 5 Despite an increased risk for sudden cardiac death, 6 transplant-free survival at 5 years is reported to range from 70 to 90%. 7 , 8 CS patients often need recurrent hospitalizations and medical care but the resource utilization and characteristics of these patients are not well understood.…”