Cardiac resynchronization therapy guided by cardiac magnetic resonance imaging: A prospective, single-centre randomized study (CMR-CRT)

Kočková, Radka; Sedláček, Kamil; Wichterle, Dan; Šikula, Viktor; Tintěra, Jaroslav; Jansova, H; Pravečková, Alena; Langová, Renata; Krýže, Lukáš; El-Husseini, Wael; Segeťová, Markéta; Kautzner, Josef

doi:10.1016/j.ijcard.2018.06.009

Cited by 17 publications

(16 citation statements)

References 29 publications

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“…CMR can also assess strain in multiple planes allowing the assessment of both radial and longitudinal strain. A recent prospective, single-center randomized study (CMR-CRT) showed the feasibility of performing an assessment of circumferential strain in order to identify the latest mechanically activated viable segment [93]. Several dyssynchrony assessment metrics have been proposed including myocardial tagging, displacement encoding with stimulated echoes, and phase contrast tissue velocity mapping.…”

Section: Dyssynchrony Assessment and Identification Of The Site Of Lamentioning

confidence: 99%

“…Unfortunately, in the STARTER study, it was only possible to deploy the lead at the target segment in 30% of patients due to issues with coronary venous anatomy and lead stability. Even in recent work where CMR was used to define the optimal pacing site, concordant LV lead positioning was only achieved in 52% of cases [93]. One approach to facilitate site selection at an achievable location subtended by a tributary of the CS is to evaluate both mechanical activation and CS anatomy.…”

Section: Multi-modality Imaging and Image Fusion Technologymentioning

confidence: 99%

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Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy

Sieniewicz

Gould

Porter

et al. 2018

Expert Review of Medical Devices

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Introduction: Cardiac resynchronization therapy (CRT) has emerged as one of the few effective treatments for heart failure. However, up to 50% of patients derive no benefit. Suboptimal left ventricle (LV) lead position is a potential cause of poor outcomes while targeted lead deployment has been associated with enhanced response rates. Image-fusion guidance systems represent a novel approach to CRT delivery, allowing physicians to both accurately track and target a specific location during LV lead deployment.Areas covered: This review will provide a comprehensive evaluation of how to define the optimal pacing site. We will evaluate the evidence for delivering targeted LV stimulation at sites displaying favorable viability or advantageous mechanical or electrical properties. Finally, we will evaluate several emerging image-fusion guidance systems which aim to facilitate optimal site selection during CRT.Expert commentary: Targeted LV lead deployment is associated with reductions in morbidity and mortality. Assessment of tissue characterization and electrical latency are critical and can be achieved in a number of ways. Ultimately, the constraints of coronary sinus anatomy have forced the exploration of novel means of delivering CRT including endocardial pacing which hold promise for the future of CRT delivery.

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Section: Dyssynchrony Assessment and Identification Of The Site Of Lamentioning

confidence: 99%

Section: Multi-modality Imaging and Image Fusion Technologymentioning

confidence: 99%

Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy

Sieniewicz

Gould

Porter

et al. 2018

Expert Review of Medical Devices

View full text Add to dashboard Cite

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“…Оба показателя влияют на достижение клинической эффективности имплантируемого устройства. Кроме того, локализация рубца должна учитываться при имплантации электрода, так как установка электрода в зону рубца снижает возможный эффект сердечной ресинхронизирующей терапии (СРТ) [181][182][183][184][185][186][187][188][189][190] 2) фракция выброса левого желудочка ≥50% [191];…”

Section: магнитно-резонансная томография сердцаunclassified

Eurasian Association of Cardiology (Eac)/ National Society of Heart Failure and Myocardial Disease (Nshfmd) Guidelines for the Diagnosis and Treatment of Chronic Heart Failure (2020)

Терещенко¹,

Жиров²,

Uskach

et al. 2020

Evrazijskij kardiologičeskij žurnal

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Disclaimer The EAC/NSHFMD Guidelines represent the views of the EAC and NSHFMD, and were produced after careful consideration of the scientific and medical knowledge, and the evidence available at the time of their publication. The EAC and NSHFMD is not responsible in the event of any contradiction, discrepancy, and/or ambiguity between the EAC/NSHFMD Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies. Health professionals are encouraged to take the EAC/NSHFMD Guidelines fully into account when exercising their clinical judgment, as well as in the determination and the implementation of preventive, diagnostic, or therapeutic medical strategies; however, the EAC/NSHFMD Guidelines do not override, in any way whatsoever, the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient’s health condition and in consultation with that patient and, where appropriate and/or necessary, the patient’s caregiver. Nor do the EAC/NSHFMD Guidelines exempt health professionals from taking into full and careful consideration the relevant official updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient’s case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations. It is also the health professional’s responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.Members of the Working Group confirmed the lack of financial support/ conflict of interest. In the event of a conflict of interest being reported, the member (s) of the Working Group was (were) excluded from the discussion of sections related to the area of conflict of interest.E.B. Wataman professor, Dr. of Sci. (Med.) (Moldova); E.K. Kurlyanskaya, Cand. of Sci. (Med.) (Belarus); A.M. Noruzbaeva professor (Kyrgyzstan); V.A. Azizov professor (Azerbaijan); Zelveyan P.A., Dr. of Sci. (Med.) (Armenia)

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“…2 The importance of guiding LV lead placement away from scar using DE-CMR is further emphasized in a large cohort of consecutive CRT candidates by Leyva et al 3 A LV lead position in scar compared to non-scar was associated with an over 6-fold increase in cardiac death and an increased risk for hospitalization and major adverse cardiovascular events. 3 A recent smaller study by Kockova et al 16 compared an CMRguided (away from scar, in late mechanical activation) LV lead placement approach with a Q-LV guided approach. Interestingly, the use of CMR did not lead to a significant reduction in cardiovascular death or hospitalization, suggestion that the use of Q-LV solely may diminish the relative benefit from CMR.…”

Section: Towards a Tailored Left Ventricular-lead Placementmentioning

confidence: 99%

“…Interestingly, the use of CMR did not lead to a significant reduction in cardiovascular death or hospitalization, suggestion that the use of Q-LV solely may diminish the relative benefit from CMR. 16 More refined approaches incorporating multimodality imaging to tailor LV-lead placement have also emerged. Pre-procedural 2D bullseye plots with information on CT, DE-CMR, and echocardiography were constructed by Bakos et al to define a late-activated segment outside scar.…”

Section: Towards a Tailored Left Ventricular-lead Placementmentioning

confidence: 99%

Integration of cardiac magnetic resonance imaging, electrocardiographic imaging, and coronary venous computed tomography angiography for guidance of left ventricular lead positioning

et al. 2018

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Cardiac resynchronization therapy guided by cardiac magnetic resonance imaging: A prospective, single-centre randomized study (CMR-CRT)

Cited by 17 publications

References 29 publications

Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy

Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy

Eurasian Association of Cardiology (Eac)/ National Society of Heart Failure and Myocardial Disease (Nshfmd) Guidelines for the Diagnosis and Treatment of Chronic Heart Failure (2020)

Integration of cardiac magnetic resonance imaging, electrocardiographic imaging, and coronary venous computed tomography angiography for guidance of left ventricular lead positioning

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