Cardiac resynchronization therapy for rate-related bundle branch block: Is there a role for His-bundle pacing?

Contractor, Tahmeed; Timothy, Pamela; Pai, Sudha M.; Mitchell, Ingrid; Bhardwaj, Rahul; Mandapati, Ravi

doi:10.1016/j.hrcr.2018.07.005

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2020

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“…There are currently three reported cases of rate‐dependent LBBB in the setting of a structurally normal heart or impaired LV systolic function in which CRT therapy or His bundle pacing was utilized to improve LVEF and clinical symptoms (Table 1). 2–4 Selective His bundle pacing or left bundle pacing could have been good alternatives in the present case.…”

Section: Figurementioning

confidence: 85%

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Rate‐dependent aberrancy and cardiac resynchronization therapy

Haseeb

Gül

2020

Pacing Clinical Electrophis

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Left bundle branch block (LBBB) can result in significant dyssynchrony in left ventricular (LV) contraction, ultimately leading to cardiac remodeling. LBBB can be rate dependent and may appear with LV systolic dysfunction. Cardiac resynchronization therapy (CRT) has been demonstrated to improve hemodynamics as well as clinical symptoms in patients with LBBB. We describe the case of a 57-year-old man who underwent CRT implantation due to exertional dyspnea, rate-dependent LBBB, and impaired left LV systolic function.

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Section: Figurementioning

confidence: 85%

“…LBBB can be rate dependent and may appear with changes in heart rate or the cardiac cycle. Relatively little is known about the etiology of rate‐dependent LBBB; however, case reports have noted improvements in clinical outcomes with traditional cardiac resynchronization therapy (CRT) or His bundle pacing 2–4 …”

Section: Figurementioning

confidence: 99%