Cardiac Protection with Targeted Drug Delivery to Ischemic-Reperfused Myocardium

Galagudza, M. M.

doi:10.5772/31586

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Isolation Of Disease-specific or Organ-specific Peptides1

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2021

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“…The assessment of cardiovascular disease risk as well as the treatment of cardiac disease will benefit from the generation of new reagents that specifically localize to heart tissue or distinct vascular beds. Targeted delivery would increase the therapeutic window of drugs effecting ion channels or contractility and potentially open avenues for gene therapy to rescue damaged tissue . For example, administration of vascular endothelial growth factor (VEGF) may improve revascularization in ischemic heart tissue, but concerns about side effects observed with systemic administration have limited its use .…”

Section: Isolation Of Disease-specific or Organ-specific Peptidesmentioning

confidence: 99%