Cardiac Paraganglioma

El-Ashry, Awad; Cerfolio, Robert J.; Singh, Satinder P.; McGiffin, David C.

doi:10.1111/jocs.12479

Cited by 17 publications

(11 citation statements)

References 24 publications

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“…An additional 2.5% mortality was reported for the immediate postoperative course. A review of individual case reports from 2014-2016, two years since Wang et al's review, shows no intraoperative mortality reported from 11 cases (12,18,19,(22)(23)(24)(25)(26)(27). Among these cases, one instance of intraoperative cardiac arrest occurred due to severe hemorrhage and one unexpected intraoperative circulatory collapse, however both ended with successful outcomes (24,26).…”

Section: Discussionmentioning

confidence: 99%

“…After recovery from surgery, benign cardiac PGs that are completely resected with negative margins have been associated with favorable outcomes in survival with low rates of tumor recurrence (18,26). For those surviving the immediate post-operative course, a 1-year survival of 98.2% and 5-year survival of 78.2% has been reported (17).…”

Section: Discussionmentioning

confidence: 99%

“…They also reported 15 cases being resected through a thoracotomy incision and only four cases not requiring the use of cardiopulmonary bypass (17). One case report indicated an attempted resection of a cardiac PG arising from the left atrium by thoracotomy, but converted to median sternotomy intraoperatively (18). Another report utilizing a thoracotomy approach resulted in severe bleeding leading to intraoperative cardiac arrest.…”

Section: Treatmentmentioning

confidence: 99%

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Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung

et al. 2018

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We present a case of unusual cardiac paraganglioma (PG) initially misdiagnosed as atypical carcinoid tumor of the lung and discuss key clinical and pathologic characteristics that guide surgical management of these rare chromaffin cell tumors. A 64-year-old female with persistent cough and back pain was found to have a 4 cm × 3 cm mass abutting multiple cardiopulmonary structures. A biopsy was performed at an outside institution and pathology reported "atypical neuroendocrine carcinoma, consistent with carcinoid". The patient was transferred to our institution and pericardial resection with right pneumonectomy was performed to excise the tumor. Histology of the mass was that of PG with multiple ethanol embolizations. Immunohistochemical examination revealed that type I (chief) cells were positive for neuroendocrine markers (chromogranin A and synaptophysin), while type II (sustentacular) cells were positive for S100. There was no evidence of atypical carcinoid tumor in the lung. PG is an entity of chromaffin cell tumors that often affects the adrenal glands and carotid body. PG rarely occurs in the thoracic region, accounting for just 1-2% of all PG. Proper diagnosis of cardiac PG is challenging owing to its rare prevalence, subtle symptoms of presentation, and the neuroendocrine histopathological features it shares with atypical carcinoids. These tumors are typically benign and are best treated by surgical resection. Our report examines the approach to appropriate diagnosis of cardiac PG vs. atypical carcinoid, preoperative management, and surgical treatment by describing successful resection through thoracotomy without the use of cardiopulmonary bypass.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

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Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung

et al. 2018

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“…recommend contrast-enhanced CT chest, abdomen and pelvis, cardiac MRI, and MIBG scan. [ 6 ] Further, Tomasian et al . report on the potential power of a combination of cardiovascular magnetic resonance with various image acquisition sequences in multiple orientations and PET-CT studies.…”

Section: Discussionmentioning

confidence: 99%

Utility of ¹⁸F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in the diagnosis of cardiac paraganglioma

Bhojwani¹,

Huang

Garg

et al. 2017

Indian J Nucl Med

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“…Non-Malignant Cardiac Tumors DOI: http://dx.doi.org /10.5772/intechopen.86944 reports or small series from large institutions. These masses include teratomas, hamartomas, fibromas, hemangiomas, paragangliomas, and mesotheliomas of the atrioventricular node [50,51]. Management is often similar to other cardiac masses and based on presenting symptoms, concern for embolic risk or obstructive physiology, and clinical risk of surgical intervention [52].…”

Section: Note: the Surgical Specimen Is From The Same Patient As The mentioning

confidence: 99%

Non-Malignant Cardiac Tumors

Eapen¹,

Malone²,

Hanna³

et al. 2020

Embolic Diseases - Evolving Diagnostic and Management Approaches

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Cardiac tumors represent an unusual clinical problem in that they are often discovered as an incidental finding during a routine echocardiogram or in the course of a work-up for a source of embolism. Malignant tumors of the heart are either defined as primary or metastatic from an extra-cardiac primary sourceregardless, the prognosis is poor. However, there are several cardiac tumors that are characterized as being non-malignant with regard to their tumor biology, but their tendencies to cause embolic or obstructive complications can be just as catastrophic despite a lack of invasiveness or potential to metastasize. The purpose of this chapter is to review the common types of non-malignant cardiac tumors with regard to their incidence, presentation, potential for complications, and management-with emphasis on surgical indications and techniques. 2 delineated as malignant and non-malignant with malignant tumors being either primary (i.e., cardiac sarcomas) or metastatic (i.e., breast carcinoma). They are distinguished from non-malignant tumors, such as myxomas and fibroelastomas, in that the latter, despite the pathologic implications of growth (i.e., valvular obstruction) and systemic embolism, lack true metastatic potential. Nevertheless, non-malignant cardiac tumors can be clinically devastating (i.e., malignant) by their tendency to cause potentially devastating, and occasionally fatal, embolic complications [5]. MethodsThe focus of this review is on non-malignant tumors. The review methods consisted of Google Scholar (https://scholar.google.com) and PubMed (https:// www.ncbi.nlm.nih.gov/pmc/) searches with emphasis on the following key words: cardiac tumors, benign cardiac masses, myxomas, fibroelastomas, and fibromas. Additional associated search terms included: surgery, diagnosis, imaging, and management. Selected references, including manuscript abstracts and full texts, were reviewed for relevance in the context of this review.

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Cardiac Paraganglioma

Cited by 17 publications

References 24 publications

Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung

Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung

Utility of ¹⁸F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in the diagnosis of cardiac paraganglioma

Non-Malignant Cardiac Tumors

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Cardiac Paraganglioma

Cited by 17 publications

References 24 publications

Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung

Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung

Utility of 18F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in the diagnosis of cardiac paraganglioma

Non-Malignant Cardiac Tumors

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Utility of ¹⁸F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in the diagnosis of cardiac paraganglioma