Cardiac Optical Coherence Tomography

Yonetsu, Taishi; Jang, Ik-Kyung

doi:10.1016/j.jacasi.2023.10.001

Cited by 2 publications

(1 citation statement)

References 98 publications

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“…Optical coherence tomography (OCT) and intravascular ultrasound (IVUS) are imaging methods used to visualize inside blood vessels, offering essential information about lesions and outcomes following stent placement in PCI. However, their invasive nature, high cost, and time-intensive procedures have hindered their widespread use, resulting in varied OCT/IVUS-guided PCI rates among countries and an overall limited penetration rate [80,81].…”

Section: Ccta In the Planning Of Pcimentioning

confidence: 99%

The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes

Tassetti,

Sfriso,

Torlone

et al. 2024

JCM

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Chronic coronary syndrome (CCS) is one of the leading cardiovascular causes of morbidity, mortality, and use of medical resources. After the introduction by international guidelines of the same level of recommendation to non-invasive imaging techniques in CCS evaluation, a large debate arose about the dilemma of choosing anatomical (with coronary computed tomography angiography (CCTA)) or functional imaging (with stress echocardiography (SE), cardiovascular magnetic resonance (CMR), or nuclear imaging techniques) as a first diagnostic evaluation. The determinant role of the atherosclerotic burden in defining cardiovascular risk and prognosis more than myocardial inducible ischemia has progressively increased the use of a first anatomical evaluation with CCTA in a wide range of pre-test probability in CCS patients. Functional testing holds importance, both because the role of revascularization in symptomatic patients with proven ischemia is well defined and because functional imaging, particularly with stress cardiac magnetic resonance (s-CMR), gives further prognostic information regarding LV function, detection of myocardial viability, and tissue characterization. Emerging techniques such as stress computed tomography perfusion (s-CTP) and fractional flow reserve derived from CT (FFRCT), combining anatomical and functional evaluation, appear capable of addressing the need for a single non-invasive examination, especially in patients with high risk or previous revascularization. Furthermore, CCTA in peri-procedural planning is promising to acquire greater importance in the non-invasive planning and guiding of complex coronary revascularization procedures, both by defining the correct strategy of interventional procedure and by improving patient selection. This review explores the different roles of non-invasive imaging techniques in managing CCS patients, also providing insights into preoperative planning for percutaneous or surgical myocardial revascularization.

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Section: Ccta In the Planning Of Pcimentioning

confidence: 99%

The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes

Tassetti,

Sfriso,

Torlone

et al. 2024

JCM

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PCSK9 and Coronary Artery Plaque—New Opportunity or Red Herring?

Barbieri,

Tumminello,

Fichtner

et al. 2024

Curr Atheroscler Rep

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Purpose of Review Although the clinical benefit of reducing low-density lipoprotein cholesterol (LDLc) in patients with coronary artery disease (CAD) is well-established, the impact on plaque composition and stability is less clear. Our narrative review aimed to assess the clinical effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on coronary plaque characteristics specifically focusing from atheroma progression to regression and stabilization. Recent Findings The combination of statin therapy and PCSK9 inhibitors (evolocumab and alirocumab) promotes plaque stability in patients following an acute coronary syndrome. The GLAGOV study highlighted the relationship between achieved LDLc levels and changes in percentage atheroma volume. Similarly, the PACMAN-AMI study concluded that the qualitative and quantitative changes in coronary plaque were associated with the levels of LDLc. Summary Assessing the severity of coronary artery stenosis and the extent of atherosclerotic burden by means of imaging techniques (e.g., IVUS, OCT and near-infrared spectroscopic) have significantly advanced our understanding of the benefits from promoting plaque regression and achieving to features of plaque stabilization through increasingly intensive lipid-lowering strategies.

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Cardiac Optical Coherence Tomography

Cited by 2 publications

References 98 publications

The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes

The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes

PCSK9 and Coronary Artery Plaque—New Opportunity or Red Herring?

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