Cardiac Myxomas: Experience Over One Decade

Patil, Nikhil P.; Dutta, Nilanjan; Satyarthy, Subodh; Geelani, Muhammad Abid; Satsangi, Deepak Kumar; Banerjee, Amit

doi:10.1111/j.1540-8191.2011.01271.x

Cited by 26 publications

(28 citation statements)

References 20 publications

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“…Our female/male ratio (14/13) in cardio myxomas differs from that of most other studies, in which this ratio varies from 1.7 to 4.4 : 1 [6, 22], including a large sample from China [7]. Only one Chinese study showed results consistent with ours; in that study, 39 of 75 patients with cardiac myxomas were women [5].…”

Section: Discussionsupporting

confidence: 57%

Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients

Long

Gao

2014

The Scientific World Journal

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Background. Heart myxoma-related embolisms commonly involve the central nervous system, but data are lacking in Chinese patients. Methods. 27 patients diagnosed with myxoma were reviewed retrospectively. Results. Among 27 patients, fourteen (51.9%) patients were women. Fifteen (55.6%) patients had brain embolisms. Rarely, patients were misdiagnosed with central nervous system vasculitis (n = 2), moyamoya disease (n = 1), and neuromyelitis optica (n = 1). We found positive associations between mRS (>3) and female gender (r = 0.873, P < 0.0001), infection (r = 0.722, P = 0.002), severe complications (r = 0.722, P = 0.002), systolic blood pressure (SBP) of <120 mmHg (r = 0.6, P = 0.018), WBC count of >10 × 109/L (r = 0.722, P = 0.002), tumour size (r = 0.866, P < 0.0001), bilateral brain lesions (r = 0.60, P = 0.018), and total anterior circulation infarction (TACI) (r = 0.667, P = 0.007). The independent relationships among these factors and outcomes could not be confirmed (P > 0.05). Conclusions. Neurologic manifestations in Chinese patients with cardiac myxoma-related stroke were complicated and multifarious. Female gender, infection, other severe complications, low SBP, tumour size, bilateral brain lesions, TACI, and high WBC counts could be associated with a poor prognosis.

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Section: Discussionsupporting

confidence: 57%

Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients

Long

Gao

2014

The Scientific World Journal

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“…[13] In another single-center study from India, of 62 patients with the cardiac myxoma, actuarial survival was 96.8 ± 1.8% at 10 years. [14] A study from Pakistan finds agreement with these observations. [15]…”

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confidence: 62%

Is the heart truly noble?

Yusuf¹

2013

South Asian J Cancer

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“…Of note, embolization and prolapse of the myxoma through valves are more common in polypoid tumours compared to round/oval myxomas (6). …”

Section: Discussionmentioning

confidence: 99%

Atrialised right ventricular myxoma in a patient with Ebstein’s anomaly

et al. 2018

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SummaryEbstein’s anomaly is a rare entity affecting around 1 in 200,000 live births and accounts for less than 1% of congenital heart diseases. Ebstein’s anomaly with an associated right-sided myxoma is extremely rare, with only one other case report found in the literature. Previous reports have also noted cases of Ebstein’s anomaly associated with left-sided myxomas. We describe a female patient with, to our knowledge, the first case of a histopathologically confirmed right ventricular myxoma in the setting of Ebstein’s anomaly.Learning points:Tall p waves (Himalayan) are associated with Ebstein’s anomaly.Large a-waves on clinical evaluation are typical of tricuspid valve obstruction or restrictive right ventricular filling.The presence of a stalk is suggestive of a myxoma.Before undertaking surgery, careful evaluation of involved structures including valvular morphology and function is essential.

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Cardiac Myxomas: Experience Over One Decade

Abstract: Biatrial involvement or multiplicity of myxomas does not mandate recurrence. Surgical excision has excellent overall survival and freedom from reoperation rates, but annual follow-up including echocardiographic surveillance is recommended as familial cases tend to recur.

Cited by 26 publications

References 20 publications

Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients

Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients

Is the heart truly noble?

Atrialised right ventricular myxoma in a patient with Ebstein’s anomaly

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