Cardiac myxoma: identification of intratumoral hemorrhage and calcification on MR images.

Masui, Takayuki; Takahashi, M; Miura, Koki; Naito, Masayasu; Tawarahara, Kei

doi:10.2214/ajr.164.4.7726036

Cited by 57 publications

(29 citation statements)

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“…The signal intensity of myxoma is similar to myocardium on T1 SE, and high on T2 SE similar to water, and shows low to high enhancement on Gd-enhanced images as described in a previous report [20]. The signal intensity of myxoma is heterogeneous on T1 SE, T2 SE, and GRE, reflecting the tissue diversity in this tumor [21], such as calcification [22,23,24] and hemorrhage. The tumor contour is clearly depicted in all cases; however, on T1 SE and T2 SE, signal arising from slow flow around the tumor precluded distinguishing of the tumor contour.…”

Section: Myxomasupporting

confidence: 69%

Role of magnetic resonance imaging for evaluation of tumors in the cardiac region

2003

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The aim of this study was to review the role of MRI in the assessment of heart neoplasm, 25 cases with heart neoplasm (10 myxoma, 6 rhabdomyoma, 5 angiosarcoma, 2 mesothelioma, 1 lymphoma, and 1 fibroma) were examined with MRI and echocardiography. Multislice T1- and T2-weighted spin-echo images and static gradient-echo images were taken in appropriate directions with electrocardiogram gating. Gadolinium enhancement was performed in 21 cases. Transthoracic echocardiography was performed in all cases. Except for the 5 patients with rhabdomyoma, the pathological diagnosis was obtained. MRI proved to be useful for tissue characterization of myxoma, angiosarcoma, mesothelioma, and fibroma in cases with tuberous sclerosis. MRI also proved to be useful for detection of the tumor, depiction of contour, relation with other cardiac structures, in cases with myxoma, angiosarcoma, mesothelioma, lymphoma, and fibroma. In the differential diagnosis, MRI provided important information in cases with myxoma, rhabdomyoma, angiosarcoma, and fibroma. In cases with tumors expanding into the mediastinum, such as mesothelioma and fibroma in this report, MRI was useful in determining the location and border. In cases with tumors adjacent to pericardium, MRI was useful in detecting pericardial invasion. Gadolinium enhancement added useful information in cases with myxoma, rhabdomyoma, angiosarcoma, and mesothelioma. The role of MRI with and without Gd enhancement differs somewhat in individual types of heart neoplasm, and adaptation must be considered in each kind of neoplasm. On the other hand, MRI is an essential examination in all cases with a cardiac mass, which has not been diagnosed, since it may provide useful information for the differential diagnosis.

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Section: Myxomasupporting

confidence: 69%

Role of magnetic resonance imaging for evaluation of tumors in the cardiac region

2003

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“…Transthoracic and transesophageal echocardiography are useful for the diagnosis of suspected myxoma and for assessing a patient's hemodynamics. However, a definitive diagnosis of myxoma is needed in patients with additional malignancies, such as the patient of the present case, and contrast CT and CMR are very helpful in this regard (3)(4)(5)(6). Features of malignant tumors visualized via CT include lymphadenopathy, pericardial effusion, the thickening of the myocardium, and the enhancement of the adjacent pericardium.…”

Section: Discussionmentioning

confidence: 85%

The Differentiation of Giant Right Atrial Myxoma from Metastatic Cancer with the Use of Multiple Imaging Modalities

et al. 2016

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Whether a cardiac tumor is primary or metastatic strongly influences the therapeutic strategy. We herein present a case of a cardiac tumor that occupied most of the right atrium which required immediate treatment in a patient with breast cancer. Multiple imaging modalities, especially computed tomography and cardiac magnetic resonance imaging, provided a precise preoperative diagnosis. We performed cardiac surgery prior to breast cancer surgery because the cardiac tumor was thought to be a myxoma rather than a metastatic cancer.

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“…Enhancement on cardiac MRI could be considered definitive to distinguish the mass from a thrombus in our case. Heterogeneous enhancement is typical of myxomas as well as the presence of thrombus on the surface and calcification within the mass 13,14) . The last two, confirmed on histopathological examination, could explain the absence of enhancement in the periphery (Fig.…”

Section: Discussionmentioning

confidence: 99%

Right Atrium Mass in a 28-Year-Old Patient with Pulmonary Embolism Taking Contraceptives

Jara‐Palomares

Serrano-Gotarredona

Haldon

et al. 2011

JAT

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We report the case of a 28-year-old woman taking contraceptives diagnosed with pulmonary embolism with a mass in the right atrium demonstrated by trans-thoracic echocardiogram that was not recognized on a previous angio-CT. Initially, it was thought to be a thrombus, but trans-oesophageal echocardiography and cardiac MRI showed data suggestive of cardiac neoplasm. Pericardial effusion and adjacent myocardial wall thickening noted on trans-oesophageal echocardiography were reported as signs that supported the possibility of malignancy, although cardiac MRI did not show wall infiltration signs. On the contrary, it demonstrated enhancement, which excludes the thrombotic nature of the mass and supports the diagnosis of neoplasm. The patient underwent surgery and biopsy proved that the mass was a myxoma. While myxomas are the most common among primary cardiac tumors, its attachment to the atrium free wall, far from the inter-atrium septum, the bi-lobed shape and accompanying pericardial effusion were atypical. J Atheroscler Thromb, 2011; 18:829-832.

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Cardiac myxoma: identification of intratumoral hemorrhage and calcification on MR images.

Cited by 57 publications

References 0 publications

Role of magnetic resonance imaging for evaluation of tumors in the cardiac region

Role of magnetic resonance imaging for evaluation of tumors in the cardiac region

The Differentiation of Giant Right Atrial Myxoma from Metastatic Cancer with the Use of Multiple Imaging Modalities

Right Atrium Mass in a 28-Year-Old Patient with Pulmonary Embolism Taking Contraceptives

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