Cardiac myxoma as a mimic: a diagnostic challenge

Frizell, Alison W.; Higgins, George L.

doi:10.1016/j.ajem.2014.08.044

Cited by 13 publications

(12 citation statements)

References 113 publications

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“…Diagnosis of cardiac myxoma is often elusive and frequently detected after a stroke as the first event [3,17]. Echocardiography proved to be readily available and a definite diagnostic modality for identifying cardiac myxoma [5]. It seems to be important to find early diagnostic clue and immediately follow echocardiography for definite diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Mechanical thrombectomy in cardiac myxoma stroke: a case report and review of the literature

et al. 2016

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Cardiac myxoma is the most common primary tumor of the heart. It is a rare cause of acute ischemic stroke and commonly not detected until after the stroke. There is no current guideline for the treatment of cardiac myxoma stroke and only a few cases of mechanical thrombectomy have been reported. We present a case of cardiac myxoma stroke in a 4-year-old boy treated with a stent-retrieval device and review the literature describing the safety and efficacy of mechanical thrombectomy in cardiac myxoma stroke. We also describe imaging features of the myxoma clot on susceptibility weighted images.

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Section: Discussionmentioning

confidence: 99%

Mechanical thrombectomy in cardiac myxoma stroke: a case report and review of the literature

et al. 2016

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“…A detailed history and physical examination are crucial for early diagnosis. Cardiovascular symptoms, including chest pain, syncope, dyspnea, and angina, are the most common features in around 67% of the patients, out of which 28% can present with acute decompensated heart failure (ADHF) [ 4 ]. Constitutional symptoms, including fever, malaise, arthralgia, and myalgia, are the second most common presentation in around 34%, while the embolic symptoms constitute up to 29% of the patients.…”

Section: Discussionmentioning

confidence: 99%

A giant left atrial myxoma causing mitral valve pseudostenosis – a mimicker

Abdelazeem

Khan

Changezi

et al. 2021

Journal of Community Hospital Internal Medicine Perspectives

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The clinical features of cardiac myxoma vary significantly from asymptomatic to severe cardiovascular complications like atrioventricular valve obstruction and thromboembolism depending on the location, size, and mobility of the tumor. Echocardiography is the diagnostic study of choice, and surgical resection is the method of choice to prevent complications. We report a case of a 47-year-old female who presented with exertional dyspnea, malaise, and weight loss. Physical examination was significant for jugular venous distension, basal crackles in lungs, 2+ pedal edema, and rumbling diastolic murmur at apex. CT of the chest revealed a hypodense filling defect in the left atrium. Transthoracic echocardiogram showed a 5.5 × 4.5 cm mobile density, likely myxoma, attached to the interatrial septum and prolapsing into the left ventricle during the diastolic phase, causing functional mitral stenosis. She underwent a resection of cardiac myxoma. The histopathology report confirmed the diagnosis of myxoma, and post-operative recovery was uneventful.

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“…In more recent reports, MRI is increasingly mentioned as a modality to better characterize tumor location and involvement preoperatively. Differences in signal intensity between myocardium, tumor/thrombus is very helpful, especially with the use of contrast agent like Gadolinium-DTPA [26][27][28]. A cine MRI sequence is a very sensitive technique to distinguish between an thrombus and a tumor, intra-cardiac or intravascular.…”

Section: Discussionmentioning

confidence: 99%

“…Once the diagnosis of cardiac myxomas made, timely surgical resection is required to prevent complications and secure immediate and long-term excellent outcomes [22,23,[24][25][26][27][28][29]. Operative mortality ranges from 0 to 3 % and recurrence rates are between 1% and 3% for sporadic myxomas [30][31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Left Atrial Myxoma as a Rare Cause of Cardiogenic Shock in Octagerians: Report of a Case and Review of the Literature

Stavros¹

2017

JOCCT

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Introduction: Cardiogenic Shock (CS) is a state of end-organ hypo perfusion due to cardiac failure. It occurs in 5% to 8% of patients hospitalized with ST-elevation myocardial infarction (STEMI). Although myocardial infarction with left ventricle failure remains the most common cause of CS, it is crucial to exclude or / and identify rare pathologies that mimic this condition. Left atrial myxoma is the most common benign primary tumor of the heart, accounting for up to 50% of primary cardiac tumors. CS or even sudden cardiac death due to myxomas may result from either complete obstruction of the mitral valve orifice or MI resulting from coronary artery emboli. Case Presentation:We report a patient admitted to our department because of syncopal episode and altered mental status due to a large left atrium myxoma. The patient was treated surgically, the myxoma was removed and the systemic manifestations of organ malperfusion were reversed. Conclusion:Identifying myxoma as a rare pathology provoking CS in octageriansrequires a high index of suspicion and diagnosis can be sometimes elusive. Differential diagnosis of new onset cardiac dysrhythmias or even CS should include this infrequent noxiousness. Clinical icon varies from asymptomatic to causing severe morbidity and sudden death, with symptoms suggestive of different cardiac entities. Surgical removal remains simplex process offering curative treatment, an excellent prognosis and low recurrences rates.

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Cardiac myxoma as a mimic: a diagnostic challenge

Cited by 13 publications

References 113 publications

Mechanical thrombectomy in cardiac myxoma stroke: a case report and review of the literature

Mechanical thrombectomy in cardiac myxoma stroke: a case report and review of the literature

A giant left atrial myxoma causing mitral valve pseudostenosis – a mimicker

Left Atrial Myxoma as a Rare Cause of Cardiogenic Shock in Octagerians: Report of a Case and Review of the Literature

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