Cardiac multiple rhabdomyomatosis: prenatal diagnosis and natural history

Spectrum and outcome of prenatally diagnosed fetal tumors

“…SD (1) TOP (1) Cardiomegaly (1) Maternal digoxin (1) CS (6) Alive and well (4) Pericardial effusion (1) Major handicap (3) Hemangioma (2) 27 (24)(25)(26)(27)(28)(29)(30) Cardiomegaly and fetal anemia (1) 38 CS (2) Alive and well (2) Turner mosaic (1) Ranula (2) 26 (23)(24)(25)(26)(27)(28) 38 SD (1) Alive and well (2) CS (1) Struma (3) 27 (22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33) Polyhydramnios (2) Amniodrainage (2) 37 (29-42) SD (2) Alive and well (2) Hydrops fetalis (1) Intra-amniotic L-thyroxine (2) CS (1) NND (1) Intravenous L-thyroxine (1) Teratoma (4) 23 …”

“…SD (5) TOP (3) Pericardial effusion (2) Amniodrainage (3) CS (11) Alive and well (11) Polyhydramnios ( Polyhydramnios (1) Amniodrainage (1) 37 (25-41) SD (4) Alive and well (6) malformation) (7)*…”

“…Major handicap (2) Sacrococcygeal Teratoma (9) 22 (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27) Polyhydramnios (3) Amniodrainage (3) 34 (29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39) CS (6) TOP (1) region (9) Hydrops fetalis (2) RFA (1) IUFD (2) Heart failure (2) The gestational age and mode of delivery varied with the site of origin and histology of the tumor. The majority of infants was delivered near term, although cases with teratoma were frequently associated with preterm birth (77.8%).…”

Comportamiento clínico de los tumores cardíacos desde el feto hasta el adulto: serie multicéntrica de 38 pacientes

“…Son benignos y regresan espontáneamente en al menos 54% de los casos, sin embargo, pueden tener indicación quirúrgica si presentan manifestaciones clínicas como compromiso hemodinámico o disrritmia refractaria, síntomas que son más frecuentes en edades tempranas 10,11,17,22 . Se pueden observar desde la época fetal y en este caso suelen ser múltiples en más de 90% de los casos 4,18 . Se asocian a esclerosis tuberosa en al menos 50%, patología que se puede transmitir de forma autosómica dominante y se caracteriza por el desarrollo de tumores llamados hamartomas que afectan cerebro, piel, riñones, esqueleto, COMPORTAMIENTO TUMORES CARDIACOS DESDE EL FETO HASTA EL ADULTO -P Arnaiz et al retina y corazón, el que está comprometido en 30-50% de los casos [19][20][21][22] .…”

Tuberous sclerosis with intracardiac rhabdomyoma in a fetus with trisomy 21: case report and review of literature

“…Although they may regress after delivery, a high rate of intra-uterine demise has been reported (Groves et al, 1992;Nir et al, 1995). Poor prognostic indicators include development of intracardiac flow obstruction, alteration of the AV-valve function with consecutive regurgitation and the frequent association with tachyarrhythmia (Soltan and Keohane, 1981;Paladini et al, 1996). Tumour growth is often biphasic, increasing in size until 32 weeks of gestation, and then regressing progressively during the first year of life (Ortiz et al, 1992).…”