Cardiac Metastatic Melanoma Investigated by Magnetic Resonance Imaging

Mousseaux, Élie; Meunier, Philippe; Azancott, Suzana; Dubayle, P; Gaux, Jean‐Claude

doi:10.1016/s0730-725x(97)00200-2

Cited by 53 publications

(22 citation statements)

References 18 publications

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“…There are no specific appearances of metastases or direct extension to the heart; malignant tumors in general have low signal intensity on T1-weighted images and high signal intensity on T2-weighted images with varying degrees of enhancement after contrast material administration, and the former are no exception. The only exception is metastatic melanoma, which may be bright on both T1-and T2-weighted images due to the presence of large amounts of paramagnetic melanin (77,78).…”

Section: Metastatic Involvementmentioning

confidence: 99%

MR Imaging of Cardiac Tumors

Sparrow

Kurian²,

Jones³

et al. 2005

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Magnetic resonance (MR) imaging is an important tool in the evaluation of cardiac neoplasms. T1-weighted, T2-weighted, and gadolinium-enhanced sequences are used for anatomic definition and tissue characterization, whereas cine gradient-echo imaging is used to assess functional effects. Recent improvements in pulse sequences for cardiac MR imaging have led to superior image quality, with reduced motion artifact and improved signal-to-noise ratio and tissue contrast. Although there is some overlap in the MR imaging appearances of cardiac tumors, particularly of primary malignancies, differences in characteristic locations and features should allow confident differentiation between benign and malignant tumors. Indicators of malignancy at MR imaging are invasive behavior, involvement of the right side of the heart or the pericardium, tissue inhomogeneity, diameter greater than 5 cm, and enhancement after administration of gadolinium contrast material (as a result of higher tissue vascularity). Concomitant pericardial or pleural effusions are rare in benign processes but occur in about 50% of cases of malignant tumors. MR imaging offers improved resolution, a larger field of view, and superior soft-tissue contrast compared with those of echocardiography, suggesting that knowledge of the MR imaging features of cardiac neoplasms is important for accurate diagnosis and management.

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Section: Metastatic Involvementmentioning

confidence: 99%

MR Imaging of Cardiac Tumors

Sparrow

Kurian²,

Jones³

et al. 2005

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307

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“…The experience with systemic chemotherapy is also sparse. Anecdotal evidence of responses to systemic therapy in heart-induced SVCS is available in advanced melanoma [4]. We did not find any report of benefit for secondline chemotherapy.…”

Section: Commentarymentioning

confidence: 57%

“…Another possibility is that of mediastinal tumours, such as thymomas [2,3], with local atrial invasion. Finally, intracardiac metastases from distant tumours such as melanomas [4], sarcomas [5], and colorectal [6] or cervix cancer [7] may also induce SVCS. This possibility has been recognised and accepted recently as the first cases of tumour infiltrating the heart as a possible cause of SVCS [7] were published in the late 1980s [8,9].…”

Section: Commentarymentioning

confidence: 99%

Heart metastases and superior vena cava syndrome

et al. 2007

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“…Although incidental cardiac metastases may be detected by CT scan, this method is limited by the poor image quality due to motion artifacts, whilst echocardiography is a more useful method. Magnetic resonance imaging may also be used [16][17][18] because melanoma produces a characteristic hyper-intense signal on T1-weighted images due to the presence of melanin in contrast with the low signal areas evidenced in other types of tumors. Moreover, histologic diagnosis can be obtained via echocardiographically guided transvenous biopsy.…”

Section: Discussionmentioning

confidence: 99%