Cardiac intracavitary metastasis of a malignant solitary fibrous tumor: case report and review of the literature on sarcomas with left intracavitary extension

Cuadrado, Marta; García-Camarero, Tamara; Expósito, Víctor; Val-Bernal, J. Fernando; Gómez-Román, Javier; Garijo, M. Francisca

doi:10.1016/j.carpath.2007.02.006

Cited by 12 publications

(7 citation statements)

References 56 publications

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“…It has been found that the frequency of cardiac metastases varies from 12% to 25% in postmortem patients who have died of malignancies and lung tumors show the most cardiac metastatic potential in the common tumors. 5 , 6 In patients such as the 1 described in this study who are completely asymptomatic, an early diagnosis of the lung tumor with the embolus extending into the LA can be challenging. CT scan and pathological examination of the lung mass would be additional tools used for cardiac imaging during the differential diagnosis of the LA mass taking into consideration that 36% to 49% of cardiac metastasis may occur in NSCLC patients.…”

Section: Resultsmentioning

confidence: 98%

An Atypically Large, Free-Floating Thrombus Extending From the Lung to the Left Atrium via a Pulmonary Vein

Wang

Li²,

Song³

et al. 2015

Medicine

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An atypically large, free-floating thrombus extending from primary pulmonary malignancy into the left atrium (LA) is a rare phenomenon. Here, we report a 61-year-old man presenting with a large mass in the lower lobe of the left lung, extending to LA via the left inferior pulmonary vein.The thrombus remained clinically silent and was detected by computed tomography (CT) and transthoracic echocardiography. To prevent life-threatening complications including systemic embolism and sudden death, the patient underwent surgical excision of the mass under cardiopulmonary bypass. Pathology of the tumor and the embolus was confirmed as moderately differentiated squamous cell carcinoma. Furthermore, immunohistochemical studies demonstrated consistency of the tumor cells in this pathological category.The patient tolerated the surgery well and his condition began to improve gradually after the operation.

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Section: Resultsmentioning

confidence: 98%

An Atypically Large, Free-Floating Thrombus Extending From the Lung to the Left Atrium via a Pulmonary Vein

Wang

Li²,

Song³

et al. 2015

Medicine

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“…The most common tumors with cardiac metastatic potential include malignant melanoma, carcinomas of the lung, esophagus and breast, malignant lymphoma, and leukemia [1][2][3]. The frequency of cardiac metastases is underestimated: varying from series to series and ranging from 12-25% of post-mortem patients who have died of malignancies [3,4]. In one series of 407 cases with cardiac metastases, 4.2% of these tumors were from a soft tisssue sarcoma primary [5].…”

Section: Discussionmentioning

confidence: 99%

“…Cardiac intracavitary metastases are infrequent and the atrium is more commonly involved than the ventricle [4]. These metastases are secondary to transvenous extension into the right atrium as a result of embolization or propagation along the vena cava.…”

Section: Discussionmentioning

confidence: 99%

A lady with excertional dyspnoea due to cardiac metastases

K¹,

Anoop²,

Np³

2017

Cancer Rep Rev

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Contrary to primary malignant cardiac tumors, metastatic tumors of the heart are relatively common. Cardiac metastases are usually the immediate cause of death in about one-third of such cases. They may cause cardiac failure, pericardial effusion and arrhythmia, with cardiac failure being the most common cause of death as a result of restrictive ventricular inflow and outflow tract obstruction, myocardial disease and pericardial constrictive disease. According to autopsy reports, cardiac metastases have been found in about 25% of patients with soft-tissue sarcoma. The incidence of cardiac metastasis has increased during recent years in view of better diagnostic tools and aggressive treatment of malignant tumors have led to longer survival of patients. Despite their increasing frequency, cardiac metastases are rarely diagnosed in living patients because other metastatic symptoms co-exist. We report a case of relapsed malignant peripheral nerve sheath tumor with symptomatic metastases to the heart. She was planned for surgery but in view of poor general condition, she was managed with palliative chemotherapy.

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“…The frequency of cardiac metastases varies from 12 to 25% of post-mortem patients who have died of malignancies. 9,10 In one series of 407 cases in which the heart or pericardium was secondarily involved with a malignant tumor, 4.2% of these tumors were from a sarcoma primary. 11 Cardiac metastases mostly appear in patients with advanced tumor disease; at this stage of disease, many patients have undergone some type of treatment for the primary tumor.…”

Section: Discussionmentioning

confidence: 99%

“…Cardiac intracavitary metastases are infrequent, with the atrium being more commonly involved than the ventricle. 10 These metastases are usually secondary to transvenous extension into the right atrium as a result of embolization or propagation along the vena cava. Our patient had no evidence of tumor in the hepatic veins or IVC on preoperative imaging; therefore, thrombectomy at the time of primary resection was not indicated.…”

Section: Discussionmentioning

confidence: 99%

Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma

Dua

Cloyd

Haddad

et al. 2014

International Journal of Surgery Case Reports

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Cardiac intracavitary metastasis of a malignant solitary fibrous tumor: case report and review of the literature on sarcomas with left intracavitary extension

Cited by 12 publications

References 56 publications

An Atypically Large, Free-Floating Thrombus Extending From the Lung to the Left Atrium via a Pulmonary Vein

An Atypically Large, Free-Floating Thrombus Extending From the Lung to the Left Atrium via a Pulmonary Vein

A lady with excertional dyspnoea due to cardiac metastases

Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma

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