Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging

Klug, Gert; Reinstadler, Sebastian Johannes; Feistritzer, Hans‐Josef; Kremser, Christian; Schwaiger, Johannes; Reindl, Martin; Mair, Johannes; Müller, Silvana; Mayr, Agnes; Franz, Wolfgang-Michael; Metzler, Bernhard

doi:10.1007/s00330-015-4022-7

Cited by 6 publications

(2 citation statements)

References 51 publications

(65 reference statements)

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“…Indeed, it was previously shown that cardiac output measured in the aorta was significantly lower during breath-holding than during free breathing [34]. This can be related to changes in systolic duration time and more generally heart rate, as previously shown between free breathing and breath-hold MRI acquisitions in patients after acute ST-segment elevation myocardial infarction [35]. In our study, we tried to avoid potential systematic changes in physiological conditions over scan time by acquiring the 3 PC MRI sequences in a different order for all subjects.…”

Section: Discussionmentioning

confidence: 81%

Comparison of 4D flow and 2D velocity-encoded phase contrast MRI sequences for the evaluation of aortic hemodynamics

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Powell

et al. 2016

Int J Cardiovasc Imaging

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The purpose of this study was to compare aortic flow and velocity quantification using 4D flow MRI and 2D CINE phase-contrast (PC)-MRI with either one-directional (2D-1dir) or three-directional (2D-3dir) velocity encoding. 15 healthy volunteers (51 ± 19 years) underwent MRI including (1) breath-holding 2D-1dir and (2) free breathing 2D-3dir PC-MRI in planes orthogonal to the ascending (AA) and descending (DA) aorta, as well as (3) free breathing 4D flow MRI with full thoracic aorta coverage. Flow quantification included the co-registration of the 2D PC acquisition planes with 4D flow MRI data, AA and DA segmentation, and calculation of AA and DA peak systolic velocity, peak flow and net flow volume for all sequences. Additionally, the 2D-3dir velocity taking into account the through-plane component only was used to obtain results analogous to a free breathing 2D-1dir acquisition. Good agreement was found between 4D flow and 2D-3dir peak velocity (differences = −3 to 6 %), peak flow (−7 %) and net volume (−14 to −9 %). In contrast, breath-holding 2D-1dir measurements exhibited indices significantly lower than free breathing 2D-3dir and 2D-1dir (differences = −35 to −7 %, p < 0.05). Finally, high correlations (r ≥ 0.97) were obtained for indices estimated with or without eddy current correction, with the lowest correlation observed for net volume. 4D flow and 2D-3dir aortic hemodynamic indices were in concordance. However, differences between respiration state and 2D-1dir and 2D-3dir measurements indicate that reference values should be established according to the PC-MRI sequence, especially for the widely used net flow (e.g. stroke volume in the AA).

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Section: Discussionmentioning

confidence: 81%

Comparison of 4D flow and 2D velocity-encoded phase contrast MRI sequences for the evaluation of aortic hemodynamics

Bollache

Ooij

Powell

et al. 2016

Int J Cardiovasc Imaging

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“…Mean interobserver difference was 0.32 ± 7.9%, mean variability was 4.6 ± 3.1% and intraclass correlation coefficient was 0.801 (KI 0.65–0.88; p < 0.001). Intra- and interobserver variabilities of LVEF measurements by our CMR lab were recently published elsewhere [28].…”

Section: Resultsmentioning

confidence: 99%

Baseline LV ejection fraction by cardiac magnetic resonance and 2D echocardiography after ST-elevation myocardial infarction – influence of infarct location and prognostic impact

et al. 2019

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Objectives The comparability of left ventricular ejection fraction (LVEF) measurements by cardiac magnetic resonance (CMR) and 2D echocardiography (2DE) early after ST-elevation myocardial infarction (STEMI) remains unclear. Methods In this study, LVEF measured by CMR and 2DE (Simpson's method) were compared in 221 patients after STEMI treated by primary percutaneous coronary intervention. 2DE image quality was systematically assessed and studies reported by an accredited examiner. Intermodality agreement was assessed by the Bland-Altman method. Major adverse cardiac events (MACE) were defined as the composite of death, myocardial infarction or hospitalisation for heart failure. Patients were followed up for a median of 40.9 months (IQR 28.1-56). Results After non-anterior STEMI, LVEF measurements by 2DE (single and biplane) were consistently underestimated in comparison to CMR (CMR 55.7 ± 9.5% vs. 2DE-4CV 49 ± 8.2% (p = 0.06), 2DE-2CV 52 ± 8% (p < 0.001), 2DE-biplane 53.5 ± 7.1% (p = 0.01)). After anterior STEMI, there was no significant difference in LVEF measurements by 2DE and CMR with acceptable limits of agreement (CMR 49 ± 11% vs. 2DE-4CV 49 ± 8.2% (p = 0.8), 2DE-2CV 49 ± 9.2% (p = 0.9), 2DEbiplane 49.6 ± 8% (p = 0.5)). In total, 15% of patients experienced a MACE during follow-up. In multivariate Cox regression analysis, reduced LVEF (< 52%) as assessed by either 2DE or CMR was predictive of MACE (2DE HR = 2.57 (95% CI 1.1-6.2), p = 0.036; CMR HR = 2.51 (95% CI 1.1-5.7), p = 0.028).Conclusions At baseline after non-anterior STEMI, 2D echocardiography significantly underestimated LVEF in comparison to CMR, whereas after anterior infarction, measurements were within acceptable limits of agreement. Both imaging modalities offered similar prognostic values when a reduced LVEF < 52% was applied. Key Points • After non-anterior STEMI, 2D-echocardiography significantly underestimated LVEF compared with cardiac MRI • An ejection fraction of < 52% in the acute post-infarct period by both 2D echocardiography and CMR offered similar prognostic values Keywords Anterior wall myocardial infarction . Magnetic resonance imaging . Cine . Echocardiography . ST-elevation myocardial infarction Abbreviation 2CV Two-chamber view 2DE 2D echocardiography 4CV Four-chamber view CMR Cardiac magnetic resonance DENSE Displacement encoding with stimulated echoes HR Hazard ratio IQR Interquartile range LGE Late gadolinium enhancement LVEF Left ventricular ejection fraction

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Is MRI equivalent to CT in the guidance of TAVR? A pilot study

et al. 2018

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Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging

Abstract: • Cine CMR and PC-CMR correlate well in healthy volunteers. • Agreement is lower in STEMI patients. • Cardiac Output should be measured with one method longitudinally. • Cardiac output decreases with age after myocardial infarction.

Cited by 6 publications

References 51 publications

Comparison of 4D flow and 2D velocity-encoded phase contrast MRI sequences for the evaluation of aortic hemodynamics

Comparison of 4D flow and 2D velocity-encoded phase contrast MRI sequences for the evaluation of aortic hemodynamics

Baseline LV ejection fraction by cardiac magnetic resonance and 2D echocardiography after ST-elevation myocardial infarction – influence of infarct location and prognostic impact

Is MRI equivalent to CT in the guidance of TAVR? A pilot study

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