Cardiac Emergencies

Htwe, Tin Han; Khardori, N.M.

doi:10.1016/j.mcna.2012.09.003

Cited by 17 publications

(6 citation statements)

References 71 publications

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“…In this regard, it is known that LPS, expressed on the external membrane of Gram-negative bacteria, represents a powerful inducer of immunity responses through the modulation of toll-like receptors 4 (TLR4) [7]; for this reason, it is widely used to reproduce inflammatory diseases, such as myocarditis [50]. Myocarditis, or inflammatory cardiomyopathy, is an inflammatory condition of the myocardium that, if prolonged, leads to cardiac injury, cardiac dysfunction, cardiomyocytes death [49] and resistance of the infectious agents to therapies [51].…”

Section: Discussionmentioning

confidence: 99%

Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction

Rocca

Bartolo

Grande

et al. 2021

International Immunopharmacology

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Section: Discussionmentioning

confidence: 99%

Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction

Rocca

Bartolo

Grande

et al. 2021

International Immunopharmacology

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“…Fatality rates of IE remain high and 2.7%of patients suffer an unexpected sudden death at 6 months during or after treatment [4]. After the near eradication of rheumatic fever in the western world, infective endocarditis accounts for the vast majority of cases of endocarditis with an incidence ranging between 1.7 and 11.2 cases per 100.000 people/year [5]. Overall, the male to female ratio is estimated at around 2 but outcomes tend to be worse in women [6].…”

Section: Introductionmentioning

confidence: 99%

The causative agents in infective endocarditis: a systematic review comprising 33,214 cases

Vogkou

Vlachogiannis

Palaiodimos

et al. 2016

Eur J Clin Microbiol Infect Dis

128

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Infective endocarditis (IE) incidence remains high with considerable fatality rates; guidelines for prophylaxis against IE are currently under review in some settings which highlights the importance of maintaining up-to-date epidemiological estimates about the most common microbial causes. The objective of this systematic review, following PRISMA guidelines, was to identify the most common microbial causes of IE in recent years. Medline was searched from January 1, 2003 to March 31, 2013 for all articles containing the term "infective endocarditis". All relevant studies reporting diagnostic results were included. Special patient subpopulations were assessed separately. A total of 105 studies were included, from 36 countries, with available data on a total of 33,214 cases. Staphylococcus aureus was found to be the most common microorganism, being the most frequent in 54.3 % of studies (N = 57) (and in 55.4 % of studies using Duke's criteria for diagnosis [N = 51]). Viridans group streptococci (VGS), coagulase-negative staphylococci (CoNS), Enterococcus spp and Streptococcus bovis were among the most common causes. S. aureus was the most common pathogen in almost all population subgroups; however, this was not the case in patients with implantable devices, prosthetic valves, or immunocompromised non-HIV, as well as in the sub-group from Asia, emphasizing that a global one-size-fits-all approach to the management of suspected IE is not appropriate. This review provides an evidence-based map of the most common causative agents of IE, highlighting S. aureus as the leading cause in the 21st century. The changing epidemiology of IE in some patient sub-groups in the last decade and the very high number of microbiologically undiagnosed cases (26.6 %) suggest the need to revisit IE prophylaxis and diagnostic strategies.

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“…Akut infektif endokardit, konjestif kalp yetmezliği, korda tendinae yırtılması, aritmiler ve embolik olaylardan dolayı akut tedavi planlanması gereken konulardandır (2,6,8,11,13) . Sürekli bakteriyemi varlığı (hemokül-türlerle saptanır), yeni bir üfürüm, septik emboli bulgusu, emboli varlığı (akut hemipleji, miyokart infarktüsü, dalak infarktüsü, periferik arteryel emboli…), ekokardiyografide vejetasyon görülmesi gibi bileşenleri içeren Duke ölçütleriyle tanı konur (2,6,8,(11)(12)(13) .…”

Section: Akut Endokarditunclassified

“…Sürekli bakteriyemi varlığı (hemokül-türlerle saptanır), yeni bir üfürüm, septik emboli bulgusu, emboli varlığı (akut hemipleji, miyokart infarktüsü, dalak infarktüsü, periferik arteryel emboli…), ekokardiyografide vejetasyon görülmesi gibi bileşenleri içeren Duke ölçütleriyle tanı konur (2,6,8,(11)(12)(13) . Ampirik antimikrobik tedavi doğal veya yapay kapak varlığına göre düzenle-nir.…”

Section: Akut Endokarditunclassified

Infectious Disease Emergencies in Adults

Öztürk¹

2017

Ankem Derg

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Cardiac Emergencies

Cited by 17 publications

References 71 publications

Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction

Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction

The causative agents in infective endocarditis: a systematic review comprising 33,214 cases

Infectious Disease Emergencies in Adults

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