Cardiac comorbidity is not a risk factor for mortality and morbidity following surgery for primary non-small cell lung cancer☆

Mishra, Pankaj; Pandey, R. K.; Shackcloth, Michael; McShane, James; Grayson, Antony D.; Carr, Martyn; Page, Richard

doi:10.1016/j.ejcts.2008.10.029

Cited by 20 publications

(18 citation statements)

References 21 publications

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“…The results of the most recent study performed on 199 patients with cardiac comorbidity and 398 patients without, are in concordance with this report [27]. There was no difference in in-hospital mortality (2.5% versus 3%; p=0.73), myocardial infarction (0.5% versus 0.3%; p>0.99), arrhythmia (15.6% versus 14.1%; p=0.62), renal failure (2% versus 1.5%; p=0.65), stroke (0.5% versus 0.3%; p>0.99), respiratory insuffi ciency (4% versus 3.3%; p=0.64), reintubation (1% versus 2.5%; p=0.35), tracheostomy (4% versus 7.8%; p=0.08), intensive care readmission (8.5% versus 6.5%; p=0.37) and length of stay (8 days versus 8 days; p=0.98).…”

Section: Infl Uence Of Lung Resection On Post-operative Lung Functionsupporting

confidence: 81%

“…There was no difference in in-hospital mortality (2.5% versus 3%; p=0.73), myocardial infarction (0.5% versus 0.3%; p>0.99), arrhythmia (15.6% versus 14.1%; p=0.62), renal failure (2% versus 1.5%; p=0.65), stroke (0.5% versus 0.3%; p>0.99), respiratory insuffi ciency (4% versus 3.3%; p=0.64), reintubation (1% versus 2.5%; p=0.35), tracheostomy (4% versus 7.8%; p=0.08), intensive care readmission (8.5% versus 6.5%; p=0.37) and length of stay (8 days versus 8 days; p=0.98). Three-year survival was similar (61.4% versus 56.2%; p=0.39) and no differences in outcome existed with different cardiac conditions [27].…”

Section: Infl Uence Of Lung Resection On Post-operative Lung Functionmentioning

confidence: 68%

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Fit for surgery? Assessment of marginal lung cancer patients

Subotic

2009

BRE

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Section: Infl Uence Of Lung Resection On Post-operative Lung Functionsupporting

confidence: 81%

Section: Infl Uence Of Lung Resection On Post-operative Lung Functionmentioning

confidence: 68%

Fit for surgery? Assessment of marginal lung cancer patients

Subotic

2009

BRE

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“…The original point of this study was to analyze a dataset in which the surgical procedure was limited to lobectomy. Other, previous studies of surgical procedures have included partial resection and segmentectomy in their analyses, in addition to lobectomy (2,5,7,8,(15)(16)(17). Accordingly, it would be difficult to obtain specific estimates of post-lobectomy survival, morbidity, and mortality outcomes from the results of these previous studies.…”

Section: Discussionmentioning

confidence: 66%

Decrease in performance status after lobectomy mean poor prognosis in elderly lung cancer patients

Kawaguchi¹,

Hanaoka²,

Oshio³

et al. 2017

J. Thorac. Dis.

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Background: Surgery remains the best treatment for obtaining cure in patients with resectable lung cancer, regardless of age. In elderly patients, however, the presumed fear of decreased performance status (PS) after lobectomy has resulted in the delivery of sub-optimal cancer surgery. Surgical decision making for such patients would become easier if post-lobectomy survival benefits and changes in PS were well defined. Methods:We reviewed patients aged 75 years or older who received lobectomy for non-small cell lung cancer (NSCLC) at our hospital between January 2004 and December 2014. Eastern Cooperative Oncology Group PS was preoperatively and postoperatively assessed in 137 patients. Patients were classified into 2 groups based on the change in PS: in Group 1, postoperative and preoperative PS were the same; in group 2, postoperative PS was less than preoperative PS. We compared the characteristics of patients in groups 1 and 2.Results: Overall 5-year survival was 47.4% in group 1 and 0% in group 2 (P<0.001). History of cardiac ischemia (P=0.001) and squamous cell carcinoma (P=0.015) were identified as significant predictors of reduced postoperative PS. Conclusions:Our results show that maintenance of PS after lobectomy is expected to be associated with a good prognosis. However, reduction of PS after lobectomy indicates an extremely poor prognosis in elderly patients with lung cancer. History of cardiac ischemia and squamous cell carcinoma are possible risk factors for decreasing PS. Thus, careful patient evaluation and selection are needed when deciding whether to use lobectomy in clinical practice.

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“…Aşamalı operasyonun savunucuları eş zamanlı ameliyatları sadece zorunlu olduğu durumlarda öner-mektedirler (24). Kalp hastalığının iyi seçilmiş hasta grubunda akciğer rezeksiyonu için risk faktörü olmadığını iddia eden yazarlar da mevcuttur (25).…”

Section: İskemi̇k Kalp Hastaliklari Ve Akci̇ğer Hastaliklariunclassified

Sımultaneous Lung Cancer And Heart Dısease

Okay¹

2016

Toraks Cer Bult

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Worldwide, especially in developed countries, prolonged life expectancy results in increasing number of age-related / associated diseases like diabetes mellitus, cardiovascular diseases, malignancies, neurological diseases, organ failures etc. in the community. Beside the numbers, planning and applying the treatment of pulmonary and cardiovascular diseases simultaneously in such patients is stil a major challenge. The knowledge and experience gained from the increasing number of patients all over the world led to the conclusion that it could be possible to treat some patient groups who would be considered as difficult or impossible to cure in the past. In this paper we evaluated the treatment process in lung diseases (especially malignancies) and cardiovascular disease seen simultaneously.Keywords: Lung cancer, heart disease, coronary artery disease, pulmonary surgery, concurrent heart lung disease, concurrent heart lung surgery ÖzetÖzellikle batıda olmak üzere tüm dünyada uzayan ortalama ömür süresi, yaşa bağlı/ilintili hastalıkların da toplumda daha sık görülmesi sonucunu doğurmaktadır. Bunlar diyabet, kalp damar hastalıkları, maligniteler, nörolojik hastalıklar, organ yetmezlikleri gibi hastalıklardır. Bu durumun yarattığı sorunlardan biri de eş zamanlı olarak görülen akciğer ve kalp damar hastalıklarının tedavisinin planlanması ve uygulanmasıdır. Tüm dünyada giderek artan sayıdaki hastalardan elde edilen bilgi ve deneyimler eskiden çok zor hatta imkansız olarak kabul edilen hasta gruplarında bile tedavi seçenekleri olabileceğini ve başarıyla uygulanabileceğini göstermektedir. Bu yazıda eş zamanlı görülen kalp-damar hastalıkları ve özel-likle maligniteler olmak üzere akciğer hastalıklarındaki tedavi süreçlerini değerlendirdik.Anahtar kelimeler: Akciğer kanseri, kalp hastalığı, koroner arter hastalığı, akciğer cerrahisi, eş zamanlı kalp akciğer hastalığı, eş zamanlı kalp akciğer cerrahisi

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Cardiac comorbidity is not a risk factor for mortality and morbidity following surgery for primary non-small cell lung cancer☆

Abstract: With careful assessment and patient selection, patients with cardiac comorbidity were not found to be at increased risk of mortality and morbidity following lung resection for primary non-small cell lung cancer in a propensity-matched population.

Cited by 20 publications

References 21 publications

Fit for surgery? Assessment of marginal lung cancer patients

Fit for surgery? Assessment of marginal lung cancer patients

Decrease in performance status after lobectomy mean poor prognosis in elderly lung cancer patients

Sımultaneous Lung Cancer And Heart Dısease

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