Cardiac-chamber-specific Fingerprints in Heart Failure with Preserved Ejection Fraction. Early Detection of Pathological Conditions by FTIR and Raman Spectroscopic Techniques
Abstract:Background The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is a matter of investigation and its diagnosis remains challenging. Although the mechanisms that are responsible for the development of HFpEF are not fully understood, it is well known that nearly 80% of patients with HFpEF have concomitant hypertension.Methods We investigated whether early biochemical alterations were detectable during HFpEF progression in salt-induced hypertensive rats, using Fourier-transformed infrared… Show more
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