Cardiac biomarkers and ultrasonography as tools in prediction and diagnosis of traumatic pericarditis in Egyptian buffaloes

Abstract

Aim:This study was designed to evaluate the cardiac biomarkers and ultrasonography in prediction and early diagnosis of traumatic pericarditis (TP) in Egyptian buffaloes.Materials and Methods:A total number of 47 buffaloes were included in the study and divided into two groups: Healthy (n=10) and diseased groups (n=37). Diseased buffaloes were admitted to the Veterinary Teaching Hospital at Zagazig University, Egypt, with a history of anorexia, sudden, and severe reduction of milk production with no response to a previous medical treatment some animals had edema at the dewlap and congestion of the jugulars. These animals were subjected to clinical examination, evaluation by hemato-biochemical analysis including cardiac biomarkers and sonography.Results:The hemato-biochemical analysis revealed leukocytosis with a shift to left and hyperfibrinogenemia (indicating inflammation). Serum cardiac biomarkers including cardiac troponin I (cTnI), cTnT, nitric oxide, creatine kinase myocardial band, and lactic dehydrogenase enzyme were significantly increased in buffaloes with TP compared with control ones. Ultrasonographically, there were hypoechoic materials with echogenic fibrin interspersed in between the pericardial sac.Conclusions:The cardiac biomarkers may be considered a useful index in the early diagnosis of TP. Moreover, ultrasonography is an excellent tool for early prediction and diagnosis of such condition.

Evaluation of Cardiac Troponin - cTnI in Cows with Traumatic Reticluo– Pericarditis

“…It helped to assess the nature of myocardial involvement and cell damage in Traumatic reticulo pericarditis affected cows. (Attia, 2016).This study was aimed at evaluating the cardiac troponin I (cTnI) using Point-of-care immunoassay i-STAT. This marker is elevated during myocardial injury or due to increased pericardial permeability.…”

Congestive heart failure in cattle; etiology, clinical, and ultrasonographic findings in 67 cases

“…Field diagnosis of such cases is very important and provides prognostic value for the animals avoiding unnecessary treatment and costs. Ultrasonography is a rapid, accurate, and low-cost diagnostic tool for heart diseases that can be easily done in the field environment with high sensitivity and specificity [ 5 , 13 , 14 ].…”

Systemic implications of metallic foreign body syndrome in dairy cattle

“…It should be noted that in the group of animals with reticulum pericarditis, the change in heart rate was much more expressive, with tachycardia in almost 90% of the affected animals. Ghanem (2010) and Attia (2016) justified tachypnea as a result of the stress associated with toxemia and septicemia caused by foreign body penetration, right congestive heart failure or lung involvement.…”

“…The association of complementary exams such as laboratory tests (hematological, biochemical and cavitary effusions) has been an important aid in the early diagnosis of the disease (Silva, 2011;Santos et al, 2020). The use of cardiac function markers such as cardiac troponin I (cTnI) and myocardial band creatine kinase (CK-MB) in ruminants has been well validated in bovines (Soares et al, 2019), goats (Ribeiro et al, 2020;Souza et al, 2020) and ewes (Souza et al, 2019), as well as in cases of traumatic pericarditis due to direct cardiac injury or in secondary involvement in cases of traumatic reticuloperitonitis (Gune et al, 2008;Attia, 2016).…”