Cardiac arrest: long-term cognitive and imaging analysis

Nunes, Belina; Pais, Joana; Garcia, Rute; Magalhães, Zita; Granja, Cristina; Silva, Carolina

doi:10.1016/s0300-9572(03)00033-9

Cited by 44 publications

(26 citation statements)

References 39 publications

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“…The severity of memory impairment in this cohort correlated with the degree of global cerebral atrophy [35]. Other imaging studies, with CT, PET and MRI, have also supported the idea that the degree of global cerebral atrophy (rather than specific anatomic regions) appears to be correlated with the severity of the cognitive deficit, including recognition and recall memory after cardiac arrest [36][37][38].…”

Section: Pathophysiology Of Cognitive Dysfunction After Cardiac Arrestsupporting

confidence: 69%

“…Nunes et al showed that in cardiac arrest patients who undergo neuropsychological testing at 20 months post-arrest, there is greater dysfunction in long-term memory (verbal more than visual spatial memory) and executive function. CT imaging completed 24 months after cardiac arrest showed a strong correlation between verbal memory and bi-caudate/bifrontal diameter ratio while third ventricle diameter was more correlated with executive dysfunction [36]. Buanes et al showed that cognitive impairment was present in 29 % of long-term CA survivors who were tested 4 years after arrest.…”

Section: The Range Of Cognitive Impairment and Dysfunction After Cardmentioning

confidence: 99%

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Cognitive and Functional Consequence of Cardiac Arrest

Perez

Samudra

Aiyagari

2016

Curr Neurol Neurosci Rep

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Cardiac arrest is associated with high morbidity and mortality. Better-quality bystander cardiopulmonary resuscitation training, cardiocerebral resuscitation principles, and intensive post-resuscitation hospital care have improved survival. However, cognitive and functional impairment after cardiac arrest remain areas of concern. Research focus has shifted beyond prognostication in the immediate post-arrest period to identification of mechanisms for long-term brain injury and implementation of promising protocols to reduce neuronal injury. These include therapeutic temperature management (TTM), as well as pharmacologic and psychological interventions which also improve overall neurological function. Comprehensive assessment of cognitive function post-arrest is hampered by heterogeneous measures among studies. However, the domains of attention, long-term memory, spatial memory, and executive function appear to be affected. As more patients survive cardiac arrest for longer periods of time, there needs to be a greater focus on interventions that can enhance cognitive and psychosocial function post-arrest.

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Section: Pathophysiology Of Cognitive Dysfunction After Cardiac Arrestsupporting

confidence: 69%

Section: The Range Of Cognitive Impairment and Dysfunction After Cardmentioning

confidence: 99%

Cognitive and Functional Consequence of Cardiac Arrest

Perez

Samudra

Aiyagari

2016

Curr Neurol Neurosci Rep

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“…There are no LOE P1-or LOE P2-studies that support the use of computed tomography (CT) imaging to predict outcome of comatose cardiac arrest survivors. Use of CT imaging is supported by 22 studies (LOE P3 992 ; LOE P4 969,984,[993][994][995][996][997][998][999][1000][1001] ; LOE P5 980,981,985,[1002][1003][1004][1005][1006] ). The timing of CT in those studies ranged from 1 hour to 20 days after sustained ROSC.…”

Section: Consensus On Sciencementioning

confidence: 99%

Part 8: Advanced Life Support

Morrison¹,

Deakin²,

Morley³

et al. 2010

Circulation

411

169

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“…Lettieri 21 Longstreth 64 Bertini 67 Bedell 77 Beuret 68 Bottiger 35 Earnest 78 Gottschalk 79 Hillis 80 Martin-Castro 81 Roewer 82 Skogvoll 36 Triano 83 Arrich 33 Dimopoulou 20 Nunes 30 Eisenberger 15 Guerot 84…”

Section: Fairmentioning

confidence: 99%