Cardiac anomalies and associated comorbidities in a large adolescent population

Fink, Daniel; Machluf, Yossy; Farkash, Rivka; Weisz, Giora; Pirogovsky, Avinoam; Tal, Orna; Dagan, Daniel; Chaiter, Yoram

doi:10.1515/ijamh-2017-0020

Cited by 3 publications

(5 citation statements)

References 33 publications

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“…The prevalence of significant valvar disease among ARF+ subjects was 2.9%, 15 times greater than among ARF-subjects (0.19%). The ratio of significant to all valvar disease was similar in both groups (1:5.5 and 1:5, respectively) [see also (36)].…”

Section: Valvar Findings Among Arf Patientsmentioning

confidence: 92%

“…It has been shown to have a stringent, high quality medical process with reliable data (34). The study population consisted of consecutive conscripts 16-19 years old, born during 1971-1993 who completed the medical profiling process during the years 1988-2011 with valid height and weight measures as previously described (35,36).…”

Section: Study Populationmentioning

confidence: 99%

“…Valvar anomalies included mitral or tricuspid insufficiency or stenosis, aortic or pulmonary insufficiency or stenosis. Valvar anomalies were divided into two groups: non-significant valvar anomalies, and significant valvar anomalies, as described previously (36).…”

Section: Definitionsmentioning

confidence: 99%

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Rheumatic Fever in Large Cohort of Adolescents in Israel

et al. 2020

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Background: Acute rheumatic fever (ARF) remains a major worldwide healthcare problem, despite its progressive decline in developed countries. The aims of our study were to estimate the prevalence of ARF among adolescents in Israel and to investigate risk factors. Methods:The study population consisted of 113,671 consecutive conscripts 16-19 years old, born during 1971-1993, who completed the medical profiling as part of the recruitment process to the IDF. ARF was diagnosed according to Jones criteria at time of illness, with confirmation relying on medical documentation and cardiologist evaluation including echocardiography.Results: The general prevalence rate of ARF was 0.12%. A downward trend was observed, from 0.19% among those born during 1971-1980 to 0.07% among those born during 1981-1993. Differences in prevalence of ARF were noted in sub-populations based on country of birth and origin-Israel, Ethiopia and the former soviet union (FUSSR). The prevalence rates of valvar disease among ARF+ and ARF-recruits were 15.7% and 0.95%, respectively. In multivariable logistic regression analyses, 4 variables were negatively associated with ARF: later birth year group, female gender, rural residence, youngest child; and 3 were positively associated with ARF: young parents, above normal BMI and valvar disease. Conclusion:Our study provides support for the documented decline in ARF prevalence and describes socio-demographic and anthropometric risk factors including the association with valvar disease and novel risk factors including above normal BMI and young parents, both warranting further investigation which might help in developing societal level prevention strategies.

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Section: Valvar Findings Among Arf Patientsmentioning

confidence: 92%

Section: Study Populationmentioning

confidence: 99%

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Rheumatic Fever in Large Cohort of Adolescents in Israel

et al. 2020

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“…Only the northern recruitment center of Israel was chosen due to its stringent assessment and reliability of its medical data ( 19 – 22 ). Further information regarding the study population, the medical process and validation of the data has been reported earlier ( 23 , 24 ).…”

Section: Methodsmentioning

confidence: 99%

“…Recruits with a diagnosis of a valvular abnormality included those with RHD and/or congenital heart disease and rarely other causes of acquired heart disease [see definitions and examples in Ref. ( 24 )].…”

Section: Methodsmentioning

confidence: 99%

Valvular Heart Disease in a Young Israeli Ethiopian Immigrant Population From the Gondar Region With Implications for Rheumatic Heart Disease

Fink

Chaiter

Menahem

et al. 2018

Front. Public Health

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BackgroundRheumatic heart disease (RHD) among Ethiopian school children was recently found to be 1.4%. Immigration of the Jewish population from the Gondar region to Israel created an opportunity for further enquiry.MethodsA cross-sectional study of the cardiac status of 113,671 adolescent recruits aged 16–19 years from the northern district of Israel who completed the medical profiling process over a 22-year period.Results140 recruits had a history of rheumatic fever (0.12%), although none from an Ethiopian origin (n = 1,719). The prevalence of valvular heart disease clinically and confirmed echocardiographically in Ethiopian recruits was not different from the total population (0.81 and 0.93%, respectively). However, the prevalence was higher in those migrating to Israel in their 13th year or older (2.09%), compared to those migrating at a younger age or born in Israel (0.49%).ConclusionThe Ethiopian teenage Israeli population from Gondar had a high rate of auscultation positive and echocardiographically confirmed valvular disease that suggested a high rate of RHD (~1.6%), despite no relevant past history. Our findings also suggested that for the younger Ethiopian immigrants or Israeli born subjects of Ethiopian origin, the improved medical care may well reduce the prevalence of valvular heart disease to that of the rest of the local population.

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Screening for Myopia-Related Retinal Changes Among Teenagers

Allon¹,

Machluf²,

Mezer³

et al. 2019

Ophthalmic Surg Lasers Imaging Retina

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BACKGROUND AND OBJECTIVE: To evaluate the relationship between spherical equivalent (SE) refractive error and myopia-related peripheral retinal changes (MPRCs) and to find the optimal cutoff for screening myopic teenagers. PATIENTS AND METHODS: The study included 2,286 myopic subjects who had a dilated fundus examination between 1998 and 2011 and SE of −4.0 diopters (D) or higher in both eyes. RESULTS: Ninety-five subjects (4.16%) had MPRCs. Two subjects (0.09%) had moderate-to-severe MPRCs. A significant correlation ( P < .0001) between SE and MPRC was found. The highest sum of sensitivity (72.63%) and specificity (73.44%) was achieved when a SE of −6.25 D in the more myopic eye was utilized as the cutoff. CONCLUSIONS: SE and MPRCs are highly associated. The optimal cutoff to detect MPRC in teenagers is −6.25 D. However, using a SE of −4.0 D as the cutoff may be the practical choice for screening due to the noninvasiveness nature and low cost of the examination. [ Ophthalmic Surg Lasers Imaging Retina. 2019;50:e311–e319.]

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Cardiac anomalies and associated comorbidities in a large adolescent population

Cited by 3 publications

References 33 publications

Rheumatic Fever in Large Cohort of Adolescents in Israel

Rheumatic Fever in Large Cohort of Adolescents in Israel

Valvular Heart Disease in a Young Israeli Ethiopian Immigrant Population From the Gondar Region With Implications for Rheumatic Heart Disease

Screening for Myopia-Related Retinal Changes Among Teenagers

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