Cardenolide glycosides from seeds of Corchorus olitorius

Nakamura, Takatoshi; Goda, Yukihiro; Sakai, Shinobu; Kondo, Kazunari; Akiyama, Hiroshi; Toyoda, Masatake

doi:10.1016/s0031-9422(98)00421-x

Cited by 47 publications

(38 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Phytochemical tests as well as characterization of fractionated compound indicate the presence of stigmasterol derivative in PECC (Nakamura, 1998;Mazumder et al, 2003b). It is already reported that various sterols (Hiremath et al, 1994(Hiremath et al, , 1999Madhavan et al, 2009) have the property to exhibit antifertility activities.…”

Section: Resultsmentioning

confidence: 99%

Fractionation of stigmasterol derivative and study of the effects ofCelsia coromandelinaaerial parts petroleum ether extract on appearance of puberty and ovarian steroidogenesis in immature mice

Pal¹,

Mazumder

Gupta

2011

Pharmaceutical Biology

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Fractionation of stigmasterol derivative and study of the effects ofCelsia coromandelinaaerial parts petroleum ether extract on appearance of puberty and ovarian steroidogenesis in immature mice

Pal¹,

Mazumder

Gupta

2011

Pharmaceutical Biology

View full text Add to dashboard Cite

“…Phytochemical tests indicate the presence of flavonoids in MECR (Rostogi and Mehrotra, 1993;Yadav et al, 2000) and steroids in MECO (Nakamura, 1998;. Since various flavonoids (Hiremath et al, 1994) and sterols (Hiremath et al, 1999) have been reported to possess antifertility activities, the anti-steroidogenic property of the MECR and MECO in male mice might be due to the presence of such compounds (Gupta et al, 2003a,b).…”

Section: Discussionmentioning

confidence: 99%

“…This was subjected to further chromatography and erysimoside (Mahato et al, 1989) Fraction eluted with chloroform: methanol (4:1) solvent system on further purification followed by chromatography afforded one compound which was identified with authentic strophanthidin (Nakamura et al, 1998) (mp, IR and comparative TLC).…”

Section: Chemical Investigation Of Mecr and Mecomentioning

confidence: 99%

“…The seed are used as purgative and leaves as demulscent, diuretic, febrifuge (infusion) and in chronic cystitis and dysuria (Chatterjee and Pakrashi, 1992). Corchorus olitorius (jute) seed is a traditional tribal medicine for birth control (Chatterjee, 1996) and found to contain steroids and glycosides (Nakamura et al, 1998;. Litterature survey reveals that no detailed study has yet been done regarding the antifertility activity of C. reflexa stem and C. olitorius seed.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of methanol extracts of Cuscuta reflexa Roxb. stem and Corchorus olitorius Linn. seed on male reproductive system of mice

Pal¹,

Gupta²,

Mazumder³

2009

Oriental Pharmacy and Experimental Medicine

View full text Add to dashboard Cite

SUMMARYThe antifertility activity of methanol extract of Cuscuta reflexa Roxb. stem (MECR) and Corchorus olitorius Linn. seed (MECO) were studied on male Swiss albino mice. The extracts were found to decrease sperm count, percentage of motile sperm and testosterone level in treated mice when compared with vehicle control after 17 days of treatment. The weight of gonads, epididymis were decreased whereas no significant changes of the body weight of mice were observed after methanol extract treatments. The fertility test showed 100% negative result in MECR and MECO treated mice at medium and high dose level of treatment. MECR and MECO in low (25 mg/kg and 15 mg/kg, respectively), medium (50 mg/kg and 20 mg/kg, respectively) and high (75 mg/ kg and 25 mg/kg, respectively) dose level caused a simultaneous fall in testicular Δ5-3β-hydroxy steroid dehydrogenase and glucose-6-phosphate dehydrogenase activities which are involved in testicular steroidogenesis. Total cholesterol and ascorbic acid content in testis were increased significantly in gonads. The activities of lactate dehydrogenase, malic dehydrogenase and ascorbic acid oxidase were reduced whereas that of carbonic anhydrase was increased significantly in the testis of MECR and MECO treated mice. All these observations indicate that the methanol extract of C. reflexa stem and C. olitorius seed produced antifertility activity in sexually matured male mice, which may be due to inhibition of gonadal steroidogenesis. This activity may be attributed due to the presence of flavonoids and steroids, respectively.

show abstract

“…1), and that these cardiac glycosides did not exist in the edible green leaves and stem at all. 8,9) During the course of the studies, we found that the seed samples collected from some regions in our country are not uniform in color (dark grayish green ~ dark grayish yellow), and that the sample consisting of mainly dark grayish green seeds contained more cardiac glycosides than those of mainly dark grayish yellow and dark grayish yellow-green seeds. 10) Thus, these results imply that dark grayish green seeds were more mature than the other colored seeds.…”

Section: Introductionmentioning

confidence: 86%

Relationship Between Cardiac Glycoside Contents and Color of Corchorus olitorius Seeds.

Matsufuji

Sakai

Chino

et al. 2001

JOURNAL OF HEALTH SCIENCE

Self Cite

View full text Add to dashboard Cite

The relationship between the cardiac glycoside contents in Corchorus olitorius seeds and the seed color was examined. The seed color was assigned a shade (color value) (L value in UCS system). The dark grayish green seeds, showing lower L value, contained more cardiac glycosides than dark grayish yellow seeds showing higher L value. When the total cardiac glycoside contents were plotted against the L values, a positive correlation (r = -0.913) was observed. Also, there was a higher content ratio of strophanthidin glycosides (erysimoside and olitoriside) in the seeds showing lower L value, while there was a lower content ratio of digitoxigenin glycosides (coroloside and glucoevatromonoside) in the seeds showing lower L value.

show abstract

Cardenolide glycosides from seeds of Corchorus olitorius

Cited by 47 publications

References 5 publications

Fractionation of stigmasterol derivative and study of the effects ofCelsia coromandelinaaerial parts petroleum ether extract on appearance of puberty and ovarian steroidogenesis in immature mice

Fractionation of stigmasterol derivative and study of the effects ofCelsia coromandelinaaerial parts petroleum ether extract on appearance of puberty and ovarian steroidogenesis in immature mice

Effects of methanol extracts of Cuscuta reflexa Roxb. stem and Corchorus olitorius Linn. seed on male reproductive system of mice

Relationship Between Cardiac Glycoside Contents and Color of Corchorus olitorius Seeds.

Contact Info

Product

Resources

About