Carcinosarcoma of Upper Aerodigestive Tract: A Case Series

Kumar, Tarun; Kothari, Kiran; Patel, Madhabhai M.; Kumar, Prabhat; Ravi, K.; Yadav, Vijay

doi:10.1007/s13193-011-0110-6

Cited by 8 publications

(14 citation statements)

References 7 publications

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“…2,3 It usually occurs in males during 6 th and 7 th decades of life. Similar to other studies, 4,5 male predominance was reported in this study with M:F ratio 4:1. Mean age was 44.8years this is much below when we compared from western data of about 60 to 70years.…”

Section: Discussion and Review Of Literaturesupporting

confidence: 92%

“…Predisposing factors are smoking, alcohol consumption, previous radiation exposure. 5 All 5 patients were chronic tobacco chewer and bidi smoker. Commonly it arises from larynx, nasal cavity, hypopharynx, oral cavity is rare site of presentation.…”

Section: Discussion and Review Of Literaturementioning

confidence: 99%

“…Here tobacco chewing is more common habit rather than smoking this might be the probable cause of increase incidence of oral cavity carcinosarcoma. 5,6 None of the patients had prior history of exposure to radiation. 60% patients were of stage III and 20% each of stage II and stage IV.…”

Section: Discussion and Review Of Literaturementioning

confidence: 99%

“…It has a male predominance with mean age of presentation in sixth decades of life with history of smoking, alcohol abuse, and radiation exposure. 4,5 Immunohistochemistry along with routine histopathology is essential in establishing the diagnosis of spindle cell carcinoma. Here we are reporting five cases of spindle cell carcinoma in head and neck region to the better understanding and awareness of rare malignancy.…”

Section: Introductionmentioning

confidence: 99%

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Carcinosarcoma of Head and Neck; Clinicopathological Characteristics, Treatment and Outcomes of Unique Neoplasm

Singh

Sharma

2017

IJRRT

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Background: Carcinosarcoma of the Head and neck is rare neoplasm with incidence of <1%. This is biphasic tumor with epithelial and mesenchymal components. Rarity of this neoplasm is major obstacle to establish proper guidelines. Only few case series and reports are available. Aim:The aim of this study was to evaluate clinicopathological characteristics, treatment and its outcome to contribute in part to the better understanding and awareness of this rare malignancy. Material and Methods:Retrospectively data of histological proven carcinosarcoma of head and neck from 2013 to 2015 was retrieved and evaluated for various parameters and also compared with both Indian and western data. Results:Total of 5 patients of carcinosarcoma were registered within selected timeframe. The mean age of 44.8years ranged from 27years to 68years. Male predominance was reported with M:F ratio 4:1.Oral cavity is most common site of tumor followed by oropharynx .Surgery is primary modality of treatment followed by adjuvant radiotherapy as per indication .Shortest follow up was 11month and longest was 31months. Only One patient was presented with recurrence. Conclusion:The diagnosis of carcinosarcoma is challenging so histopathology along with immunohistochemistry is needed for appropriate diagnosis. Oral cavity seems to be the most common site with younger age group in present study which is supported by other Indian studies. Future studies are needed to define the geographical variation with clinicopathological character as well as treatment protocol for this relatively rare entity.

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Section: Discussion and Review Of Literaturesupporting

confidence: 92%

Section: Discussion and Review Of Literaturementioning

confidence: 99%

Section: Discussion and Review Of Literaturementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Carcinosarcoma of Head and Neck; Clinicopathological Characteristics, Treatment and Outcomes of Unique Neoplasm

Singh

Sharma

2017

IJRRT

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“…Most commonly it arises from larynx, nasal cavity, hypopharynx, esophagus, trachea, oral mucosa. It has a male predominance with mean age of presentation in sixth decades of life with history of smoking, alcohol abuse, and radiation exposure [4,5]. Immunohistochemistry along with routine histopathology is essential in establishing the diagnosis of spindle cell carcinoma.…”

Section: Introductionmentioning

confidence: 99%

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2017

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Carcinosarcoma of Tongue with Predominant Osteosarcomatous Component

Rao

Jain

Murthy

et al. 2018

Indian J Surg Oncol

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Carcinosarcoma is exceedingly rare in the oral cavity and shows presence of both carcinomatous and sarcomatous components. We report a case of carcinosarcoma of tongue in a 51-year-old male with predominant osteosarcomatous and squamous cell carcinoma components. There was no evidence of regional or systemic metastatic disease. This case represents the first reported example of this unusual neoplasm with a predominant osteosarcomatous component, arising in the tongue.

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Carcinosarcoma of Upper Aerodigestive Tract: A Case Series

Cited by 8 publications

References 7 publications

Carcinosarcoma of Head and Neck; Clinicopathological Characteristics, Treatment and Outcomes of Unique Neoplasm

Carcinosarcoma of Head and Neck; Clinicopathological Characteristics, Treatment and Outcomes of Unique Neoplasm

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Carcinosarcoma of Tongue with Predominant Osteosarcomatous Component

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