Carcinosarcoma of the Extrahepatic Bile Duct Presenting with Stone-like Radiological Findings

Abstract

A 73-year-old woman was referred to our hospital due to epigastralgia and jaundice. The radiological findings showed a stone-like tumor in the extrahepatic bile duct. The patient was initially thought to have adenocarcinoma of the bile duct based on the findings of a pathological examination of the bile duct biopsy specimen and underwent pancreaticoduodenectomy; the final diagnosis of the lesion was so-called carcinosarcoma of the extrahepatic bile duct. She died of liver metastasis six months after the surgery. This case suggests that surgical resection is not adequate for achieving a radical cure, and the optimal treatment for extrahepatic bile duct carcinosarcoma should be established immediately.

Aggressive behavior of anaplastic undifferentiated carcinoma arising from the hilar bile duct

“…In the distal bile duct, 10 resected cases with undifferentiated features have been reported (Table 2) [7,9,10,[18][19][20][21][22][23][24]. Most tumors were sarcomatoid-type carcinoma, and there was no anaplastic-type carcinoma.…”

Rapid progression of sarcomatoid carcinoma of the common bile duct

“…[3,[6][7][8][9][10][11][12][13][14]. Tumors in the CBD may have a better prognosis owing to theirA B Immunohistochemical staining (×200).…”