Carcinome muco-épidermoïde intra-osseux des mâchoires

Serpa

J Oral Maxillofac Pathol

et al. 2016

Central mucoepidermoid carcinoma (CMC) of the jaw bones is a rare malignant salivary gland tumor of unknown pathogenesis, comprising about 4% of all mucoepidermoid carcinomas (MECs). Most cases are histologically classified as a low-grade tumor and radiographically appear as a well-defined unilocular or multilocular radiolucent lesion. Block resection or wide local excisions are the treatment of choice and patients usually show a good overall prognosis although a long-term follow-up is necessary. This report describes a case of a 28-year-old male with MEC in the posterior region of the mandible and discusses its clinical, radiographic and histopathological findings. Although rare, CMC may be considered a differential diagnosis in cases of proliferative and osteolytic lesions in the oral cavity even when its clinical and/or radiographic findings do not suggest malignancy.

Section: Discussionmentioning

confidence: 99%

Central mucoepidermoid carcinoma radiographically mimicking an odontogenic tumor: A case report and literature review

Serpa

J Oral Maxillofac Pathol

et al. 2016

Med Buccale Chir Buccale

“…Le carcinome muco-épidermoïde (CME) est une tumeur maligne des maxillaires qui représente 1 à 3 % des cancers des voies aéro-digestives supérieures et entre 15 % à 30 % des tumeurs malignes des glandes salivaires [1,2]. Cette tumeur identifiée par Loos en 1913 doit être connue de l'odontologiste et du chirurgien mais aussi du pathologiste puisque l'attitude thérapeutique est dictée par son diagnostic [2,3].…”

Section: Introductionunclassified

Le carcinome muco-épidermoïde du palais : présentation de deux cas et revue de la littérature

Bridonneau

Quinque

Zink

et al. 2017

Résumé -Introduction :Le carcinome muco-épidermoïde (CME) est une tumeur maligne rare qui se développe à partir des glandes salivaires. Son traitement comporte la chirurgie associée ou non à la radiothérapie en fonction du grade histologique. Observation : Nous rapportons les cas de découverte fortuite de CME chez deux jeunes filles adressées par leur chirurgien-dentiste traitant. L'examen a mis en évidence une lésion maculaire ou papulaire de couleur violacée localisée au niveau du palais dur. L'examen anatomopathologique a confirmé le diagnostic d'un CME de bas grade dans les deux cas. Une tomographie volumique par faisceau conique, un scanner cervico-thoracoabdomino-pelvien et une imagerie par résonance magnétique ont été réalisés dans le cadre du bilan d'extension. Le traitement a consisté dans les deux cas en une exérèse de la lésion avec marge. Une prothèse obturatrice a été mise en place en per-opératoire pour fermer la communication bucco-nasale. Dans un cas, une reconstruction de la perte de substance par un lambeau de rotation palatin a été effectuée au bout de 2 ans de suivi. Discussion : La découverte d'un CME chez des jeunes patients est rare. Ces deux observations permettent de faire le point sur la prise en charge de ce type de cancer en fonction des caractéristiques histologiques. Abstract -Palatal mucoepidermoid carcinoma: diagnosis and multidisciplinary care. Introduction:Mucoepidermoid carcinoma (MEC) is a malignant tumor of the salivary glands. Depending on the histological grading, treatment requires surgery with or without radiotherapy. Observation: Two cases of MEC in young female patients are described. The clinical examination revealed a purplish lesion located on the hard palate. The histological examination confirmed the diagnosis of a low-grade MEC. Cone beam computed tomography, a cervicothoracic CT scan and a MRI were performed in order to control lesion extension and exclude a metastatic evolution. Resection of the lesion was performed and oro-nasal communication was immediately closed by a prosthetic obturator. In one case, no recurrence was observed, and closure of the oro-nasal communication was performed two years later by a palatal rotation flap. Discussion: MEC in adolescents is rare. These observations are opportunity to review the management of this type of cancer with regard to histological typing.

An unusual case of intraosseous mucoepidermoid carcinoma of the mandible

Wang

et al. 2018

Medicine

Rationale:Mucoepidermoid carcinoma (MEC) is the most common primary salivary gland malignancy. Ectopic MEC can occur in any part of the body, however, only 2% to 4% of MEC could be detected in the jaw, which is named intraosseous mucoepidermoid carcinoma (IMC). IMC is usually a low-grade carcinoma. Uni- or multilocular radiographic lesions should be differential diagnosed with ameloblastoma, odontogenic cysts, and glandular odontogenic cyst (GOC). Radical surgery may prefer for a favorable prognosis. Whereas IMC can recur long after the operation, a long-term follow-up system should be implemented. Owing to its rarity and controversial issues, we report a case report and review the literature to discuss its clinical features, treatments, radiological, and histological characteristics.Patient concerns:The patient presented with a 2-month history of mild pain in the lower left posterior jaw without history of surgery or trauma to the mandible.Diagnoses:Routine postoperative pathology showed that the mass was consistent with a mandibular mucoepidermoid carcinoma.Intervention:Radical surgery and digital mandibular reconstruction were performed.Outcome:Postoperative imaging showed that the height of the mandible and the symmetry of the mandible were satisfactory. The patient was also satisfied with her appearance. Follow-up has been established.Lessons:Effective surgical treatment allows patients to have a favorable prognosis. A long-term follow-up system should be practiced, because local recurrences and regional metastasis could happen even after decades.