Carcinoma of thoracic Œsophagus and cardia. A review of 405 cases

Miller, Charles F.

doi:10.1002/bjs.18004921704

Cited by 128 publications

(39 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The papers by Collis (1957), Ellis, Jackson, Krueger, Moersch, Clagett, and Gage (1959)~ Nakayama (1yj9), Mullard (1960), Le Roux (1961) ~ Miller (1962) ~ Logan (1963) ~ and Gunnlaugsson, Wychulis, Roland, and Ellis (1970) all demonstrate a similar theme. With determined effort and the experience which comes from handling these cases in large numbers, the growths can be removed with a low level of morbidity and a mortality which is not too oppressing.…”

mentioning

confidence: 62%

Surgical treatment of carcinoma of the oesophagus and cardia

Collis

1971

Journal of British Surgery

View full text Add to dashboard Cite

SUMMARYExperience in the management of a personal series of 837 cases of carcinoma of the oesophagus and cardia is described. It is evident from this that the subject is not a static one. Improvement is occurring and there are good reasons to expect this to continue. The aspects affected by this improvement include morbidity, mortality, the well-being of patients, and the long-term survival. Unfortunately, in the majority of cases, treatment is only palliative, but palliation is good and it relieves the patient of his main symptom-dysphagia.In view of the great benefits which good palliation provides, no treatment can be considered as satisfactory unless the relief of symptoms is of a high standard.It is maintained that too much emphasis has hitherto been placed on long-term survival, which is only possible in the minority of cases.Bearing all factors in mind a strong case can be made for the overall surgical plan in the management of growths affecting the middle and lower parts of the oesophagus. all demonstrate a similar theme. With determined effort and the experience which comes from handling these cases in large numbers, the growths can be removed with a low level of morbidity and a mortality which is not too oppressing. It is also clear that improvement is still continuing. Operative mortality varies from 5 to 30 per cent and late results range between 10 and 25 per cent of operative survivors still alive at 5 years after operation. It seems reasonable to conclude that unless the operative mortality can be brought down to approximately 10 per cent and unless morbidity is low there is a tendency for radiotherapy to be preferred to surgery.Several workers have attempted to improve longterm results by combining surgery with radiotherapy and reports of the outcome of such efforts have been appearing during the past 20 years (Cliffton and

show abstract

mentioning

confidence: 62%

Surgical treatment of carcinoma of the oesophagus and cardia

Collis

1971

Journal of British Surgery

View full text Add to dashboard Cite

show abstract

“…This accounts for a high rate of resection margin positivity, when limited longitudinal resections are employed, even with negative frozen section biopsy margins. 162 Extensive studies [163][164][165] support the view that the proximal extent of resection should ideally be 10 cm above the macroscopic tumour and 5 cm distal to it, when the oesophagus is in its natural state. Local recurrence can be minimised in this situation by the use of postoperative radiotherapy 166 and this should be considered in SCC, particularly when the proximal level of the tumour is high.…”

Section: Standards Of Tumour Resectionmentioning

confidence: 99%

Guidelines for the management of oesophageal and gastric cancer

Allum

Griffin

Watson

et al. 2002

Gut

291

183

View full text Add to dashboard Cite

“…Our findings are in an agreement with previous studies in which half of the patients got relief from dysphagia by radiotherapy. However, in half of these patients the dysphagia reoccurred within 6 months which in almost every patient indicated a terminal phase (14).…”

Section: Discussionmentioning

confidence: 96%

“…The 5-year survival rates after both surgery and radiotherapy are less than 10% in most series. The prognosis has not been significantly improved during the last decades (2,3,(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). Different treatment modalities with cytostatics combined with surgery or radiotherapy and a combination of different irradiation techniques have been studied, but all these treatments are still under investigation (16)(17)(18)(19)(20).…”

mentioning

confidence: 99%