Carcinoma of the Urachus: Report of Two Cases and Review of the Literature

Urachal carcinoma: Clinicopathologic features and long‐term outcomes of an aggressive malignancy

“…Similar to other studies, we observed that neither age nor gender were predictors of outcome. [3][4][5] To our knowledge, the current study presents the first multivariate analysis of predictors of malignancy in patients with clinically diagnosed urachal masses. We observed that, if a patient was older than age 55 years at diagnosis, then the probability that their urachal mass was malignant tripled.…”

“…carcinoma is generally poor, because their tumors often are not diagnosed until late in the course of the disease. [2][3][4][5] In this article, we review all urachal carcinomas that were diagnosed and treated at the Mayo Clinic over the last 50 years. We present a comprehensive description of urachal carcinomas and describe several novel findings, including, 1) predictors of malignancy for clinically diagnosed urachal masses, 2) prognostic factors for urachal cancer-specific survival, 3) a simplified pathologic staging system, 4) a presentation of the natural history of urachal carcinomas treated at different disease stages, and 5) evidence of the efficacy of salvage treatment for urachal cancers that recur locally after primary treatment.…”

Use of Polypropylene Mesh for Abdominal Wall Defect in Surgery of Advanced Urachus Carcinoma

“…Since local recurrence and spread to the regional lymph nodes are frequent [3], surgery should be as radical as possible. The en bloc removal of the tumor with the bladder and the soft tis sues of the abdominal wall and pelvic lymph node dis section seems to be the best choice of treatment to date [1,4]. As a result of extensive resection, however, as in our case, a large defect may remain in the midabdominal wall.…”

“…, results were discouraging [1,3]. Since local recurrence and spread to the regional lymph nodes are frequent [3], surgery should be as radical as possible.…”

“…Carcinoma of urachus, which arises from the vestigial allantois, has a tendency towards progressive infiltration of the abdominal wall from the early stage of growth [1], Excision of the tumor, therefore, usually involves the muscles of the abdominal wall. Insofar as the tumor is confined to the inner layer of the rectus abdominis, it may be possible to resect the tumor while conserving the outer layer of the muscles and, at least, the anterior rec tus sheaths.…”