Carcinoma of the Urachus Associated with Urachal Adenoma

Ng, Kounis; Newman, P.; Price-Thomas, J. M.

doi:10.1111/j.1464-410x.1991.tb15115.x

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Cited by 10 publications

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“…5 A urachal adenocarcinoma arising in a pre-existing adenoma has previously been reported. 6 As far as we are aware, this is the first report of a urachal tumour at the stage of carcinoma in situ. We raise the possibility that, as in colonic adenocarcinomas, 7 there is a biological continuum of behaviour of glandular neoplasms in the urachus from benign to malignant.…”

Section: Discussionmentioning

confidence: 77%

Stage 0 mucinous adenocarcinoma in situ of the urachus.

et al. 1998

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Adenocarcinomas of the urinary bladder are rare (1-5% of bladder tumours) and of notoriously poor prognosis. About one third of such tumours arise in urachal remnants related to the bladder. This is believed to be the first report of in situ change in the urachal remnant. The patient presented with mucusuria and computed tomography showed a typical urachal cyst. After excision the cyst was found to contain mucinous adenomatous epithelium but without invasion of the basal lamina. Pathological stage is the best prognostic indicator in urachal tumours. Prompt investigation and management of mucusuria may allow the diagnosis of urachal tumours in this preinvasive stage. (J Clin Pathol 1998;51:483-484)

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Section: Discussionmentioning

confidence: 77%