Carcinoma of the small bowel.A complication of regional enteritis

Abstract

The 35th and 36th cases of adenocarcinoma arising in small bowel affected with regional enteritis are presented. The pathology of all reported cases is reviewed. An association between regional enteritis and carcinoma of the small bowel is suggested.

Small bowel adenocarcinoma in Crohn disease: CT-enterography features with pathological correlation

“…This condition is associated with a worse prognosis than sporadic small bowel adenocarcinoma [40]. Therapy is limited, and surgery when feasible is the only hope for cure.…”

Adenocarcinoma in Crohn’s disease: the pathologist’s experience in a tertiary referral centre of inflammatory bowel disease

“…1,2 Also, small bowel adenocarcinoma arising in the setting of CD is a well-known complication, with an increased risk compared to the general population. This explains the high stage of these tumours at the time of surgery: [6][7][8] up to 35% of adenocarcinomas are diagnosed at stage IV. 3,4 The most problematic issue is that neoplasia and inflammation can induce the same occlusive symptoms.…”

Small Bowel Adenocarcinoma in Crohn’s Disease

“…4,5 This diagnostic difficulty contributes to the fact that nearly 30-35% of small adenocarcinomas diagnosed in patients with Crohn's Disease are stage IV by the time of diagnosis. 6,7 In this study, we describe 29 patients with small bowel adenocarcinoma complicating Crohn's disease in order to further characterize the clinicopathologic features of this lethal entity and to update a previous series from our institution published in 1991. 5…”