Carcinoma of the penis Experience with 153 cases

Johnson, Douglas E.; Fuerst, Donald E.; Ayala, Alberto G.

doi:10.1016/0090-4295(73)90368-3

Cited by 59 publications

(16 citation statements)

References 14 publications

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“…Although all Grade-I patients are currently alive, the presence of tumors of both grades (I and II) among the surviving patients suggests a lack of correlation between grade and survival. Johnson reached a similar conclusion in a study of 153 cases (22). On the other hand, Ornellas and Cubillas found histological grade to be a significant adverse prognostic factor for lymph nodes metastasis and survival (16,23).…”

Section: Discussionsupporting

confidence: 52%

Locally advanced penile carcinoma: classic emasculation or testis-sparing surgery?

Gonzaga-Silva¹,

Lima²,

Tavares³

et al. 2012

Int. braz j urol.

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Purpose:The study evaluates the clinical and pathological fi ndings of 16 patients with locally advanced penile carcinoma (PC) submitted to emasculation, and discusses questions related to the usefulness of bilateral orchiectomy. Materials and Methods: Between 1999 and 2010, 172 patients with PC were treated. Sixteen (9%) underwent emasculation. Data were retrieved from the institution's database including age, ethnicity, date of surgery, residential setting, level of schooling, time to diagnosis, type of reconstruction, complications, tumor stage and grade, vascular and perineural invasion along with invasion of corpus cavernosum, corpus spongiosum, testicles, scrotum and urethra. Results: A total of 16 patients (average: 63.1 years) with locally advanced PC were included. All were illiterate or semiliterate rural dwellers and 87% were white. The time to diagnosis was 8-12 months. The mean follow-up time was 31.9 months (1-119). By the time of the last follow-up, only seven patients (43.75%) were alive. Tumors were pT4 (n = 6), pT3 (n = 8), pT2 (n = 2), Grade I (n = 5) and Grade II (n = 11). The histopathological examination revealed invasion of the urethra (n = 13), scrotum (n = 5) and testicles (n = 1). The surgical margin was positive in one patient. Six patients (37.5%) had vascular invasion and 11 (68.7%) had perineural invasion. Currently, only one of the former is alive. Conclusions: The fi nding of focal microscopic testicular infi ltration in only one of 32 testicles, even in the presence of clinically apparent scrotal invasion, suggests that emasculation without bilateral orchiectomy is a safe treatment option for patients with locally advanced PC.

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Section: Discussionsupporting

confidence: 52%

Locally advanced penile carcinoma: classic emasculation or testis-sparing surgery?

Gonzaga-Silva¹,

Lima²,

Tavares³

et al. 2012

Int. braz j urol.

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show abstract

“…Unfortunately, circumcision and local excision of the tumor are associated with high recurrence rate [2, 3, 4, 5, 6, 7]and at present they are not recommended for routine management of penile carcinoma [3, 8]. These circumstances forced investigators to search more effective and acceptable alternatives to surgery.…”

Section: Discussionmentioning

confidence: 99%

Is Conservative Organ–Sparing Treatment of Penile Carcinoma Justified?

Gotsadze

Matveev²,

Zak

et al. 2000

European Urology

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“…Several series in the literature indicate that delayed treatment is not prejudicial since no detrimental effect on 5-year survival rates have been documented among tomic crossover of lymphatics of the penis is well-estab lished, and bilateral drainage is therefore the rule [6, 9,13,26]. Bilateral lymphadenectomy is recommended in patients presenting palpable adenopathy in conjunction with the primary tumor, provided that morbidity factors (over 70 years of age, obesity, leg edema) are absent.…”

Section: Management Of Regional Lymph Nodesmentioning

confidence: 99%

“…In fact, 20-25% of patients initially N i develop bilateral metastatic nodes. The ana N0 [2,13], delayed inguinal adenopathy must be consid ered as a metastasis and lymphadenectomy performed.…”

Section: Management Of Regional Lymph Nodesmentioning

confidence: 99%