Carcinoma of the Breast in Men

Abstract

Male breast cancer is an uncommon disease of uncertain etiology. We describe a 66-year-old man who presented with a palpable mass in the left breast with associated nipple inversion. Mammographic images demonstrated a spiculated mass within the subareolar left breast at the palpable area of concern. Sonographic evaluation demonstrated a hypoechoic mass within the subareolar left breast at the location of the mammographic abnormality. The patient underwent an excisional biopsy and was subsequently diagnosed with high-grade invasive ductal carcinoma, the most common histologic type of carcinoma identified in men.

Diagnosis, Prognosis, and Management of Breast Cancer in an 81-Year-Old Male Patient

“…The most common form of breast cancer in men is invasive ductal carcinoma [3]. This specific pathology is characterized by initial development in the ducts of the breast followed by an invasion of surrounding tissues [4][5].…”

Invasive Ductal Carcinoma of the Breast in an Elderly Male Veteran with Solid Papillary Growth Pattern: A Case Report

“…The etiology of male breast cancer is not well known compared to female breast cancer, but there are several known risk factors that have been implicated which include both genetic and congenital, prior radiation exposure, alterations of the estrogen-testosterone ratio, and occupational hazard [5,6]. Of all the known etiologies, the greatest risk factor is concomitant Klinefelter's syndrome [6].…”

“…The different histologic types of carcinoma identified in female breast cancer have been seen in male, but the most common histologic finding is invasive ductal carcinoma that makes up approximately 90% [5,6]. An important pathologic characteristic of male breast cancer is higher rate of hormone receptor expression compared to with female counterparts.…”

“…It is estimated that about 90% of male breast cancer express estrogen-receptor positivity and 80% express progesteronereceptor positivity [6,7]; this is true in our patient. The treatment modality is dependent on histologic type of cancer as well as the degree of spread of the disease at the time of diagnosis [5]. Patients presenting with nonmetastatic disease, the current recommended treatment modality is modified radical mastectomy with axillary lymph node dissection [6,7].…”