Carcinoma espinocelular in situ tratado con imiquimod al 5%

Martínez, Silvestre; Boz, J. del; Vera, Ángel; Sanz, Andrés; Crespo, V.

doi:10.1016/s0001-7310(06)73397-x

Cited by 4 publications

(3 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1, 2c, 3a), in contrast to BD which tends to appear as a plaque-like lesion [1, 6]. (2) These 9 lesions grew in less than 2 months time, while BD usually grows over several years [5, 6]. (3) Almost all BD are positive for p16 staining [14, 15], while in our 9 cases it was negative.…”

Section: Discussionmentioning

confidence: 87%

“…Although these lesions could be considered as verrucous BD, we do not believe this to be the case because of the following reasons: (1) Our lesions were verrucose and exophytic, with a similar clinical morphology to a wart or a cutaneous horn (fig. 1, 2c, 3a), in contrast to BD which tends to appear as a plaque-like lesion [1, 6]. (2) These 9 lesions grew in less than 2 months time, while BD usually grows over several years [5, 6].…”

Section: Discussionmentioning

confidence: 99%

“…Solar radiation, some subtypes of human papillomavirus (HPV) and the exposure to arsenic have been involved in its etiology [1,2,3,4]. BD clinically appears as a well-defined erythematous lesion, with a slightly hyperkeratotic surface that usually presents slow growth [5, 6]. Diverse histological varieties of BD have been described: psoriasiform, atrophic, acanthotic, verrucous-hyperkeratotic, pigmented and clear cell BD [5,6,7].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

‘Bowenoid Wart’: Wart with Bowenoid Histological Changes?

et al. 2008

View full text Add to dashboard Cite

Introduction: Cases of lesions that simulate Bowen’s disease have been previously described in the literature. Case Report: Nine exophytic verruca-like lesions with histological findings of Bowen’s disease (BD) are described. All cases had a rapid growth, and were located on the face and neck of elderly patients with chronic solar skin damage. We carried out p16 immunohistochemical staining using the immunoperoxidase technique, which was negative in all cases. Discussion: We think that these 9 lesions are only histologically mimicking BD, and could be a subtype of verruca (‘bowenoid wart’). These lesions could be provoked by nononcogenic human papillomavirus (HPV), as in other cases previously described. The p16 staining was negative in all cases, in contrast with most BD cases. It would be interesting to study whether positive p16 staining is related to oncogenic HPV, whereas negative p16 staining could be associated with low or nononcogenic HPV; thus, more studies are needed.

show abstract