Carcinoma Buccal Mucosa with Metastasis to Left Adrenal

Suhag, Virender; Bs, Sunita; Sridhar, P.S.; Rautray, D.; Singh, Hariqbal; Kallur, KG; Nagaraj, KR

doi:10.1016/s0377-1237(11)80027-4

Cited by 6 publications

(7 citation statements)

References 8 publications

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“…Only one case has been reported till today. Suhag V et al reported synchronous metastasis of adrenal gland in a case of locally advanced SCC of buccal mucosa [4]. Our reporting is second case with adrenal metastasis and first case as metachronous adrenal deposit.…”

Section: Discussionsupporting

confidence: 53%

“…Rarely other sites of distant metastases have been reported; including brain, pericardial cavity, liver, lung, thyroid, bone and bone marrow. Suhag V et al reported first case of adrenal gland metastasis reported in 2011 [4]. We report probably the second case of adrenal metastasis in advanced buccal mucosa till date.…”

Section: Introductionmentioning

confidence: 54%

“…Distant metastasis occurs in approximately 15% to 20% of patients who eventually die of their disease. However, SCC of buccal mucosa is the most common oral cancer in men and the third most common oral cancer in women in India; and accounts for up to one-third of all tobacco-related cancers [4,5]. The patient may present with pain, bleeding, trismus and cervical lymphadenopathy.…”

Section: Discussionmentioning

confidence: 99%

“…Lymph node metastasis occurs in 9-30% patients during the course of treatment [6]. In oral cavity cancer, local recurrence is more common than regional recurrence, and has been reported between 23-32% [4].…”

Section: Discussionmentioning

confidence: 99%

“…Neck node metastasis, extra-capsular spread and lymphovascular space invasion increase the risk for distant metastases. Distant metastases generally have poor prognosis, with ninety percent mortality within 1 to 16 month (median 3 months) of the evidence of distant metastasis [4]. Distant metastases typically manifest themselves in the lung, bones, liver and skin.…”

Section: Discussionmentioning

confidence: 99%

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An Unusual Adrenal Gland Metastasis in a Case of Squamous Cell Carcinoma of Buccal Mucosa

Manir

Chakraborty

Biswas

et al. 2017

IJMPCR

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The majority of oral cavity cancers presents as localized disease and remain localized until late in the course of their development. Distant metastasis is very rare in carcinoma of buccal mucosa and has a very dismal prognosis. Distant spread is either related to uncontrolled local disease or inadequate local treatment. Lungs and bones are common site for metastases. Extensive metastatic workup should be considered in locally advanced buccal mucosa patients, who either defaulted complete treatment or have an uncontrolled loco-regional relapse. We report a case of unusual adrenal metastasis from Squamous Cell Carcinoma (SCC) of buccal mucosa. 42 years old lady initially presented with cT2N1M0 SCC of buccal mucosa (left) underwent radical surgery followed by post-operative Radiotherapy. After eight months of follow up she developed local relapse. After an initial response to salvage systemic chemotherapy, patient discontinued chemotherapy. After 6 months of discontinuation patient had gradually increasing abdominal pain. Contrast Enhanced Computer Tomography Scan (CECT) showed Left adrenal mass with para-aortic lymph node. Other investigations were normal. CT guided Fine needle Aspiration Cytology (FNAC) showed metastatic deposit of squamous cell origin. Patient is being treated with Tab Gefitinib and supportive medications. Case Study

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Section: Discussionsupporting

confidence: 53%

Section: Introductionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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