Carcinoid Tumors

Pinchot, Scott N.; Holen, Kyle D.; Sippel, Rebecca S.; Chen, Herbert

doi:10.1634/theoncologist.2008-0207

Cited by 221 publications

(221 citation statements)

References 112 publications

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“…Clinical presentation, tumor aggressiveness and metastatic potential, and the prognosis depend upon the primary location [19].…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Treatment of Gastroenteropancreatic Neuroendocrine Tumors: Current Data on a Prospectively Collected, Retrospectively Analyzed Clinical Multicenter Investigation

Niederle

2011

The Oncologist

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Background. The aim of this prospectively collected, retrospectively analyzed clinical investigation was to describe "unmasked" clinical symptoms and methods of diagnosis, treatment, and short-term follow-up of gastroenteropancreatic neuroendocrine tumors (GEPNETs) diagnosed during 1 year in Austria.Methods. In total, 277 patients with GEP-NETs were documented. All tumors were immunhistochemically defined according to recently summarized criteria (World Health Organization, European Neuroendocrine Tumour Society). A standardized questionnaire comprising 50 clinical and biochemical parameters (clinical symptoms, mode of diagnosis, treatment, follow-up) was completed by attending physicians.Results. The most common initial symptoms were episodes of abdominal pain, diarrhea, weight loss, gastrointestinal bleeding, flushing, and bowel obstruction. Overall, 48.1% of tumors were diagnosed by endoscopy, 43.7% were diagnosed during surgery, 5% were diag-

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“…Clinical presentation, tumor aggressiveness and metastatic potential, and the prognosis depend upon the primary location [19].…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Treatment of Gastroenteropancreatic Neuroendocrine Tumors: Current Data on a Prospectively Collected, Retrospectively Analyzed Clinical Multicenter Investigation

Niederle

2011

The Oncologist

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“…(15) In a report published in 1985, the PS and the carcinoid tumor were located in the left lower lobe. (16) In the case presented here, the PS and the carcinoid tumor were located in different lobes, but both were located in the right lung.…”

Section: Discussionmentioning

confidence: 65%

“…When a carcinoid tumor occurs in the bronchopulmonary system, it can manifest as recurrent episodes of pneumonia, cough, hemoptysis, and chest pain. (16) In the case reported here, the major symptom experienced by the patient was hemoptysis, and there was a history of recurrent pneumonia. These two characteristics are common to PS and to carcinoid tumors, a fact that made the preoperative diagnosis of PS difficult, because the symptoms of the patient were attributed to the neoplasm and to chronic obstruction.…”

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confidence: 69%

Tumor carcinoide e sequestro pulmonar

et al. 2012

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Pulmonary sequestration is defined as a mass of lung tissue separated from the tracheobronchial tree and irrigated by an anomalous systemic artery. It is rarely seen in conjunction with lung neoplasms. We report the case of a 39-year-old female patient diagnosed with a carcinoid tumor, located in the intermediate bronchus and accompanied by bronchiectasis in the right lower lobe. The patient underwent thoracotomy for the resection of the affected area. During surgery, she presented with significant hemorrhage resulting from the transection of the anomalous artery that irrigated an intralobar pulmonary sequestration, which was located in right lower lobe and had not been identified in pre-operative examinations.Keywords: Bronchopulmonary sequestration; Hemorrhage; Carcinoid tumor. ResumoO sequestro pulmonar é definido como uma massa de tecido pulmonar separada da árvore traqueobrônquica e irrigada por uma artéria sistêmica anômala. Sua associação com neoplasias pulmonares é rara. Relatamos o caso de uma paciente de 39 anos com o diagnóstico de tumor carcinoide localizado no brônquio intermediário, associado a alterações caracterizadas como bronquiectasias em lobo inferior direito. A paciente foi submetida à toracotomia para ressecção da área acometida e, durante a cirurgia, apresentou hemorragia importante decorrente da transecção da artéria anômala que nutria o sequestro pulmonar intralobar localizado em lobo inferior direito, não identificado nos exames pré-operatórios. Depending on its pleural covering, PS is classically divided into intralobar and extralobar. An intralobar PS (ILPS) share the pleural covering with the rest of the lung, whereas an extralobar PS (ELPS) is completely covered by its own visceral pleura. Descritores(5) Although the extralobar form is well defined as a congenital abnormality, the intralobar form has a controversial pathogenesis, with some evidence indicating that, in many cases, it is an acquired disease. (6,7) Accounting for approximately 75% of all cases of PS, ILPS is more common in the lower lobes and on the left, involving the posterior basal segment. (5,8) Its arterial supply is nearly always derived from the aorta or from one of its branches, typically one of a large diameter. Venous drainage is via the pulmonary veins into the left atrium, creating a left-to-left shunt. In a minority of cases, drainage is via the inferior vena cava or via the azygos system. (9) In the case presented here, the PS was located in the right lower lobe and the blood supply came from an anomalous branch derived from the thoracic aorta.Cases of ILPS typically occur in adolescents and young adults with a history of recurrent infections of the respiratory tract, hemoptysis, and dyspnea. Some ILPS patients develop cardiac symptoms, which are a consequence of the lefthemoptysis. In the preoperative investigation, a CT scan of the chest revealed a lesion in the intermediate bronchus (Figure 1), as well as cystic bronchiectasis in the right lower lobe (Figure 2). Fiberoptic bronchoscopy confirme...

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“…They are usually found in the gastrointestinal tract (55%) or the bronchopulmonary tract (10%). 8 Atypical carcinoma of the larynx occurs in more than 90% of the cases in the supraglottic area, prevailing on the aryepiglottic fold, arytenoids and larynx side of epiglottis. It is more common in males (3:1 ratio), especially smokers.…”

Section: Discussionmentioning

confidence: 99%

Case report of atypical carcinoid tumors of the larynx

Alkhaliah

Almajed

Alkhalifah

et al. 2018

Int J Community Med Public Health

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Neuroendocrine tumors (NET) of the larynx are considered one of the rare disease; they represent only 1% of the laryngeal tumors. These tumors are very aggressive with a high rate of metastases. Diagnosis is done by computed tomography and confirmed by histopathological examination. Neuroendocrine tumors can be classified into four types based on histopathology: typical carcinoid tumors, atypical carcinoid tumors, small cell neuroendocrine tumors and paragangliomas. Atypical carcinoid tumor of the larynx is considered rare in occurrence. We report a rare laryngeal neuroendocrine tumor case.

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Carcinoid Tumors

Cited by 221 publications

References 112 publications

Diagnosis and Treatment of Gastroenteropancreatic Neuroendocrine Tumors: Current Data on a Prospectively Collected, Retrospectively Analyzed Clinical Multicenter Investigation

Diagnosis and Treatment of Gastroenteropancreatic Neuroendocrine Tumors: Current Data on a Prospectively Collected, Retrospectively Analyzed Clinical Multicenter Investigation

Tumor carcinoide e sequestro pulmonar

Case report of atypical carcinoid tumors of the larynx

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