Carcinoid of the duodenum: A report of six cases

Abstract

Duodenal carcinoid tumors are rare. Six cases of primary duodenal carcinoid tumors are presented. Analysis of these cases indicates that the radiographic appearance can vary from a benign-appearing intramural submucosal mass lesion to a large bulky ulcerating lesion. All cases in this series followed a benign course. One patient has survived over 30 years with proven regional and hepatic metastases. This patient showed regression of the duodenal lesion following embolization for control of severe hemorrhage.

Primary carcinoid of the duodenum: Detection and characterization by magnetic resonance imaging

“…Duodenal carcinoids are rare and comprise less than 5% of carcinoid tumors of the gastrointestinal tract (3.4) and less than 3% of all duodenal tumors (5). Duodenal carcinoid tumors have an appearance ranging from a benign mural mass to a larger bulky ulcerating lesion (5). The MR findings of a focal mass with intermediate to high signal intensity on T2-weighted images and marked enhancement after contrast were suggestive of the diagnosis in this patient and are similar to the findings of smaller neuroendocrine tumors in other locations, such as the pancreas and liver (6).…”

Sporadic duodenal polyps: classification, investigation, and management

“…The small intestine was the most predominant site (44.7 %), with the distribution mainly in the ileum, less frequently in the jejunum, and rarely in the duodenum [117]. Duodenal carcinoids comprise 2 % -3 % of all duodenal tumors [118]. Duodenal carcinoids may occur in any part of the duodenum and are usually slow-growing and benign.…”

“…They can be single or multiple and can vary in size. They may be seen as an irregularity or deformity of the mucosal wall, or may form an intraluminal polypoid mass and ulcerate [118]. Forceps biopsy is advocated in all lesions.…”

Massive bleeding from duodenal carcinoid treated by gastroduodenal artery embolization*

“…Primary carcinoid tumors in the duodenum are extremely rare. In 1984, Clements and Roche [1] described six cases of the primary carcinoid tumors of the duodenum, most of which had a benign course. However, periampullary neoplasm with necrosis or ulceration occasionally may cause life-threatening bleeding, which requires emergency pancreaticoduodenoctomy [2].…”