Carcinoid heart disease

Gustafsson, Björn; Hauso, Øyvind; Drozdov, Ignat; Kidd, Mark; Modlin, Irvin M.

doi:10.1016/j.ijcard.2008.02.019

Cited by 116 publications

(130 citation statements)

References 58 publications

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“…El riesgo quirúrgico aunque en disminución, sigue siendo mayor que el de la valvulopatía reumática o degenerativa. Un hecho constante es que la progresión de la insuficiencia cardiaca aumenta aún más la mortalidad perioperatoria 12 .…”

Section: Discussionunclassified

“…Las prótesis biológicas presentarían una serie de ventajas como la no necesidad de anticoagulación con menor riesgo de sangrado sobre todo en aquellos con disfunción hepática o que deben ser sometidos a procedimientos complementarios; falta de real evidencia que demuestra degeneración significativa producto de las hormonas con estas válvulas; diferencia entre la expectativa de vida del paciente v/s duración de la bioprótesis 1,12 .…”

Section: Discussionunclassified

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Síndrome carcinoide y compromiso valvular cardiaco, a propósito de 2 casos: Report of two cases

et al. 2014

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Section: Discussionunclassified

Síndrome carcinoide y compromiso valvular cardiaco, a propósito de 2 casos: Report of two cases

et al. 2014

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“…Patients with elevated 5-hiaa levels remain at risk for carcinoid heart disease 33,[39][40][41][42]74,75 . Case series of patients with carcinoid heart disease have described an association between elevated 5-hiaa and the development and pathogenesis of carcinoid heart disease 33,[39][40][41][42] .…”

Section: -Hiaamentioning

confidence: 99%

“…Case series of patients with carcinoid heart disease have described an association between elevated 5-hiaa and the development and pathogenesis of carcinoid heart disease 33,[39][40][41][42] . Therapy with ssa reduces circulating serotonin levels and may stabilize the progression of carcinoid heart disease 74,75 .…”

Section: -Hiaamentioning

confidence: 99%

Consensus Recommendations for the Diagnosis and Management of Well-Differentiated Gastroenterohepatic Neuroendocrine Tumours: A Revised Statement from a Canadian National Expert Group

et al. 2010

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Well-differentiated neuroendocrine tumours (netspreviously called "carcinoid tumours") are relatively rare tumours originating from the diffuse neuroendocrine system; they are found most often in the bronchial or gastrointestinal systems. In Canada, gastroenterohepatic nets represent less than 0.25% of oncology cases. Because of the relative rarity of these tumours, diagnostic and therapeutic approaches vary and are often based on individual physician experience. A number of European and North American groups have developed consensus guidelines for the diagnosis and management of well-differentiated gastroenterohepatic nets, and in 2006, Canadian consensus guidelines were published by a Canadian expert group. The updated and expanded current Canadian guidelines are based on a consensus meeting held in Paris, France, in 2008 and are based on the most current literature.

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“…It is associated with valvular lesions in humans with carcinoid tumors, or in those receiving serotonergic drugs [2,4]. Long term administration of 5-HT also develops valvular lesions in rats [3,5]. Myxomatous mital valve disease (MMVD) is one of the most common heart disease in dogs [3].…”

Section: Introductionmentioning

confidence: 99%

Serum serotonin concentration in lean and obese dogs with myxomatous mitral valve disease

Kim

Park

Hyun

et al. 2016

Korean Journal of Veterinary Research

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Abstract:The aim of the present study is to investigate the potential influence of obesity as a factor in 5-hydroxytryptamine (5-HT) concentration in myxomatous mitral valve disease (MMVD) dogs. Fifty-five client-owned dogs were enrolled in a randomized trial. Dogs were classified by echocardiography into healthy (control), mild, and moderate to severe MMVD groups. Each group was subclassified by using a 9-point body condition score (BCS); lean (BCS 5-6/9) and obese groups (BCS 7.5-9/9). Dogs with moderate to severe MMVD had lower serotonin (5-HT) concentrations than the control group (p = 0.03). Dogs with moderate to severe MMVD (p = 0.017) had lower serum 5-HT concentrations than the control group in the obese group (BCS 7.5-9/9). Significant difference was found between the lean and obese groups (p = 0.015) which are not consider severe in the MMVD group. These results suggested that 5-HT concentration was decreased with the increasing severity of MMVD, and obesity might be taken into consideration when interpreting the serotonin concentration in MMVD dogs.

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Carcinoid heart disease

Cited by 116 publications

References 58 publications

Síndrome carcinoide y compromiso valvular cardiaco, a propósito de 2 casos: Report of two cases

Síndrome carcinoide y compromiso valvular cardiaco, a propósito de 2 casos: Report of two cases

Consensus Recommendations for the Diagnosis and Management of Well-Differentiated Gastroenterohepatic Neuroendocrine Tumours: A Revised Statement from a Canadian National Expert Group

Serum serotonin concentration in lean and obese dogs with myxomatous mitral valve disease

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