“…Finally, three studies failed to meet the inclusion criteria, as the primary form of treatment in these studies was radical surgery rather than chemoradiation. Ultimately, 21 studies remained for full inclusion in this literature review (Figure 1) (Fontana et al , 1991; Tanum et al , 1992; Goldman et al , 1993; Holm and Tanum, 1996; Tanum and Holm, 1996; Allal et al , 1998, 2003, 2004; Grabenbauer et al , 1998; Bonin et al , 1999; Indinnimeo et al , 1999, 2000a, 2000b, 2001; Wong et al , 1999; Holm et al , 2001; Le et al , 2005; Alvarez et al , 2006; Nilsson et al , 2006; Bruland et al , 2008; Ajani et al , 2009). …”