Carboxyhemoglobin measurement by hospitals: Implications for the diagnosis of carbon monoxide poisoning

Hampson, Neil B.; Scott, Karen L.; Zmaeff, Jennette L.

doi:10.1016/j.jemermed.2005.09.010

Cited by 31 publications

(22 citation statements)

References 7 publications

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“…Moreover, not all hospitals possess such equipment and must therefore send samples to outside facilities, which can significantly delay the diagnosis. Hampson et al found that less than half of the hospitals they surveyed in the Pacific Northwest, where CO poisoning is common, have the laboratory capability to measure COHb and the time required to obtain a result averaged 15 hours longer when samples were sent elsewhere (8). There are more rapid and less invasive diagnostic tests for carbon monoxide exposure, such as a breath analyzer.…”

Section: Discussionmentioning

confidence: 99%

Finding needles in a haystack: A case series of carbon monoxide poisoning detected using new technology in the emergency department

Chee

Nilson

Partridge

et al. 2008

Clinical Toxicology

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Introduction. The diagnosis of carbon monoxide poisoning can be difficult because the symptoms are nonspecific and may mimic other illnesses. If carbon monoxide poisoning is suspected, the standard test at this time is venous or arterial carboxyhemoglobin levels. A new device, the Rad-57 pulse CO-oximeter (Masimo Inc.), can measure carboxyhemoglobin levels non-invasively at emergency department triage. Methods. The pulse CO-oximeter was utilized in our emergency department triage to measure carboxyhemoglobin levels on all patients. A retrospective chart review was then conducted to identify all patients with elevated levels. Case Series. Out of an estimated 74,880 patients who had their SpCO measured and documented at triage, seven patients who presented with vague complaints were diagnosed with occult carbon monoxide poisoning. Their diagnosis was facilitated by the non-invasive pulse COoximeter, which measured their carboxyhemoglobin levels when the standard vital signs were also documented at triage. Conclusions. The non-invasive pulse CO-oximeter could be a major triage tool for identifying unsuspected carbon monoxide poisoning among patients with nonspecific symptoms.

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Section: Discussionmentioning

confidence: 99%

Finding needles in a haystack: A case series of carbon monoxide poisoning detected using new technology in the emergency department

Chee

Nilson

Partridge

et al. 2008

Clinical Toxicology

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“…hospital ERs, can measure COHb and/or administer HBO. For example, in one recent study, only 44% of acute care hospitals had the capability of measuring COHb [64].…”

Section: Treatmentmentioning

confidence: 99%

Carbon monoxide intoxication: An updated review

Prockop

Chichkova

2007

Journal of the Neurological Sciences

631

371

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“…Determination of HO COHb percentage of the arterial blood was performed gasometrically by Blood Gas Analyzer (Bayer Rapidlab 865, USA) according to the method described by Hampson et al [13].…”

Section: Determination Of Serum Uric Acid and Creatininementioning

confidence: 99%

Role of Heme Oxygenase, Leptin, Coenzyme Q10 and Trace Elements in Pre-eclamptic Women

Abo-Elmatty

Badawy²,

Hussein³

et al. 2012

Ind J Clin Biochem

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The objective of this study to evaluate heme oxygenase (COHb), leptin and coenzyme Q10 (CoQ10) in pre-eclamptic women. Also Zinc, copper, Iron, total iron binding capacity, Ferritin and uric acid were assessed. 120 female subjects were included in this study. They were divided into, 60 female with normal pregnancy attending the outpatient clinic, 60 pre-eclamptic patients were recruited from obstetrics and gynaecology department Elkasr El-Aini hospital. The results showed that in preeclampatic group, leptin level was significantly increased while COHb and CoQ10 was significantly decreased. It is concluded that hemeoxygenase, leptin and coenzyme CoQ10 can be considered as new markers for prediction of pre-eclampsia.

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Carboxyhemoglobin measurement by hospitals: Implications for the diagnosis of carbon monoxide poisoning

Cited by 31 publications

References 7 publications

Finding needles in a haystack: A case series of carbon monoxide poisoning detected using new technology in the emergency department

Finding needles in a haystack: A case series of carbon monoxide poisoning detected using new technology in the emergency department

Carbon monoxide intoxication: An updated review

Role of Heme Oxygenase, Leptin, Coenzyme Q10 and Trace Elements in Pre-eclamptic Women

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