1991
DOI: 10.1016/1043-6618(91)90042-v
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Carbonic anhydrase inhibitors are antiarthritic in the rat

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Cited by 7 publications
(7 citation statements)
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“…It has been found that carbonic anhydrase activity enhanced the stimulation of prostaglandin E 2 for bone resorption [12]. Some groups found that the carbonic anhydrase inhibitor acetazolamide inhibited bone resorption [30,31]. They suggested that the carbonic anhydrase inhibitors played an antiarthritic role by inhibiting bone resorption.…”
Section: Discussionmentioning
confidence: 99%
“…It has been found that carbonic anhydrase activity enhanced the stimulation of prostaglandin E 2 for bone resorption [12]. Some groups found that the carbonic anhydrase inhibitor acetazolamide inhibited bone resorption [30,31]. They suggested that the carbonic anhydrase inhibitors played an antiarthritic role by inhibiting bone resorption.…”
Section: Discussionmentioning
confidence: 99%
“…Nolan et al found that carbonic anhydrase inhibitors, including cetazolamide, ethoxzolamide, methazolamide and dichlorphenamide, reduced paw edema and attenuated the deterioration of the joints of rats with adjuvant arthritis. They suggested that the carbonic anhydrase inhibitors combat arthritis by inhibiting bone resorption 22. The increased bone resorption is a characteristic of AS 23, 24.…”
Section: Discussionmentioning
confidence: 99%
“…Nolan et al also found that carbonic anhydrase inhibitors including acetazolamide, ethoxzolamide, methazolamide, and dichlorphenamide reduced paw edema and attenuated joint deterioration in rats with adjuvant arthritis. They suggested that the carbonic anhydrase inhibitors played an antiarthritic role by inhibiting bone resorption [23]. These investigations demonstrated a functional role for carbonic anhydrase in the mediation of hormone-stimulated bone resorption [24].…”
Section: Discussionmentioning
confidence: 99%