Carbon Quantum Dots from Pomelo Peel as Fluorescence Probes for “Turn-Off–On” High-Sensitivity Detection of Fe3+ and L-Cysteine

Zhang, Dianwei; Zhang, Furui; Wang, Fenghuan; Liu, Huilin

doi:10.3390/molecules27134099

Cited by 19 publications

(10 citation statements)

References 37 publications

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“…The CDs-based fluorescent biothiols assay was illustrated by (1) the CD–metal ion pair system [ 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 ] and (2) CD-nanocomposites [ 125 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 ,…”

Section: Representative Mechanism Of Cds-based Fluorescent Biothiols ...mentioning

confidence: 99%

“…In general, the interaction of emissive CDs with metal ions (Hg 2+ , Ag + , Cu 2+ , Fe 3+ , and Au 3+ ) led to fluorescent quenching, which recovers due to the effective interaction of biothiols with metal ions, as shown in Figure 2 A [ 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 120 , 121 , 122 , 123 , 124 ]. In fact, the metal ions present in the CD–metal ion pair strongly bind with biothiols via an M n+ –S interaction to release emissive CDs and exhibit fluorescence recovery.…”

Section: Representative Mechanism Of Cds-based Fluorescent Biothiols ...mentioning

confidence: 99%

“…Towards metal complex-prompted detection of Cys, Hcy, and GSH, the CD–Fe 3+ complex was proposed, as detailed in the following. Zhang et al prepared the blue emissive CDs (CQDs; average size = 5.5 nm; λ em = 410 nm at excitation of 310–350 nm; PLQY = 17.31%) from green pomelo peel via the one pot hydrothermal synthesis method and employed them in progressive detection of Fe 3+ and L-Cys, as shown in Figure 9 [ 115 ]. The complexation occurred between CQDs and Fe 3+ , which led to PL quenching.…”

Section: Cd–metal Ion Pair For Selective Quantification Of Biothiolsmentioning

confidence: 99%

“…Hence, it can be regarded as remarkable sensory research. Based on previous reports [ 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 ], it can be concluded that CD-metal ion pairs can act as a unique sensory array towards multi-channel fluorescent assays of biothiols [ 123 , 124 ].…”

Section: Cd–metal Ion Pair For Selective Quantification Of Biothiolsmentioning

confidence: 99%

“… The detection principle for Fe 3+ and L-Cys based on CQDs (reproduced with the permission from Ref. [ 115 ]). …”

Section: Figurementioning

confidence: 99%

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Review on Carbon Dot-Based Fluorescent Detection of Biothiols

Shellaiah

Sun

2023

Biosensors

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Biothiols, such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a vital role in gene expression, maintaining redox homeostasis, reducing damages caused by free radicals/toxins, etc. Likewise, abnormal levels of biothiols can lead to severe diseases, such as Alzheimer’s disease (AD), neurotoxicity, hair depigmentation, liver/skin damage, etc. To quantify the biothiols in a biological system, numerous low-toxic probes, such as fluorescent quantum dots, emissive organic probes, composited nanomaterials, etc., have been reported with real-time applications. Among these fluorescent probes, carbon-dots (CDs) have become attractive for biothiols quantification because of advantages of easy synthesis, nano-size, crystalline properties, low-toxicity, and real-time applicability. A CDs-based biothiols assay can be achieved by fluorescent “Turn-On” and “Turn-Off” responses via direct binding, metal complex-mediated detection, composite enhanced interaction, reaction-based reports, and so forth. To date, the availability of a review focused on fluorescent CDs-based biothiols detection with information on recent trends, mechanistic aspects, linear ranges, LODs, and real applications is lacking, which allows us to deliver this comprehensive review. This review delivers valuable information on reported carbon-dots-based biothiols assays, the underlying mechanism, their applications, probe/CDs selection, sensory requirement, merits, limitations, and future scopes.

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Section: Representative Mechanism Of Cds-based Fluorescent Biothiols ...mentioning

confidence: 99%

Section: Representative Mechanism Of Cds-based Fluorescent Biothiols ...mentioning

confidence: 99%

Section: Cd–metal Ion Pair For Selective Quantification Of Biothiolsmentioning

confidence: 99%

Section: Cd–metal Ion Pair For Selective Quantification Of Biothiolsmentioning

confidence: 99%

“… The detection principle for Fe 3+ and L-Cys based on CQDs (reproduced with the permission from Ref. [ 115 ]). …”

Section: Figurementioning

confidence: 99%

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Review on Carbon Dot-Based Fluorescent Detection of Biothiols

Shellaiah

Sun

2023

Biosensors

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Facile Synthesis of Carbonized Polymer Dots and their Applications in Security Inks, Sensing, Light Emitting Diodes, and UV Shielding Films

Guo,

Xu,

et al. 2024

ChemNanoMat

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Carbonized polymer dots (CPDs) have received much attention in recent years owing to their cost‐effective synthesis, high resistance to photobleaching, environmental friendliness, and excellent biocompatibility. However, the aggregation‐induced fluorescence quenching is a great obstacle to its applications. In this work, the highly fluorescent CPDs are prepared by a facile hydrothermal method assisted by polyethylene glycol (PEG) as the surface passivation agent, where phthalic acid and ethylenediamine are used as carbon and nitrogen source, respectively. Meanwhile, five types of PEG species are applied to prepare five CPDs to investigate PEG on optical properties of the resultant CPDs, among which the best quantum yield reaches 57.0%. The promising applications of CPDs as fluorescent inks, sensors, light emitting diodes, and UV shielding films have been demonstrated. Overall, our contribution here develops a facile and accessible route for the synthesis of CPDs and further demonstrates its versatile applications.

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Modification of Carbon Dots for Metal‐Ions Detection

Fan

Liu

et al. 2023

ChemistrySelect

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It is very appealing to develop cheap, highly sensitive and efficient metal ion fluorescence sensors as traditional instrument methods are inherently costly and time‐consuming. Carbon dots (CDs) are widely used for sensing metal ions, attributing to their merits of good biocompatibility, low toxicity, easy surface modification and excellent photostability. This article reviewed the research progress of CDs as metal ion sensors in recent years, and studied their modification methods and detection performances. Finally, the challenges and opportunities of CDs as metal ion sensors were also analyzed. This article is expected to provide inspiration and help for researchers focusing on CDs as metal ion sensors.

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Carbon Quantum Dots from Pomelo Peel as Fluorescence Probes for “Turn-Off–On” High-Sensitivity Detection of Fe3+ and L-Cysteine

Cited by 19 publications

References 37 publications

Review on Carbon Dot-Based Fluorescent Detection of Biothiols

Review on Carbon Dot-Based Fluorescent Detection of Biothiols

Facile Synthesis of Carbonized Polymer Dots and their Applications in Security Inks, Sensing, Light Emitting Diodes, and UV Shielding Films

Modification of Carbon Dots for Metal‐Ions Detection

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