Carbon nanotubes: Evaluation of toxicity at biointerfaces

Mohanta, Debashish; Patnaik, Soma; Sood, Sanchit; Das, Nilanjan

doi:10.1016/j.jpha.2019.04.003

Cited by 227 publications

(132 citation statements)

References 68 publications

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“…Nevertheless, possible toxicity of nanomaterials limits CNTs' medical applications [24], even though reports to date are scarce and inconclusive, e.g., for the neurotoxic effects of CNTs [25], or CNTs formation of reactive oxygen species [26]. There are more reports on the lack of adverse effects of CNTs than on their long-term toxicity [24].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy

et al. 2019

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Carbon nanotubes are proposed for reinforcement of the hydroxyapatite coatings to improve their adhesion, resistance to mechanical loads, biocompatibility, bioactivity, corrosion resistance, and antibacterial protection. So far, research has shown that all these properties are highly susceptible to the composition and microstructure of coatings. The present research is aimed at studies of multi-wall carbon nanotubes in three different combinations: multi-wall carbon nanotubes layer, bilayer coating composed of multi-wall carbon nanotubes deposited on nanohydroxyapatite deposit, and hybrid coating comprised of simultaneously deposited nanohydroxyapatite, multi-wall carbon nanotubes, nanosilver, and nanocopper. The electrophoretic deposition method was applied for the fabrication of the coatings. Atomic force microscopy, scanning electron microscopy and X-ray electron diffraction spectroscopy, and measurements of water contact angle were applied to study the chemical and phase composition, roughness, adhesion strength and wettability of the coatings. The results show that the pure multi-wall carbon nanotubes layer possesses the best adhesion strength, mechanical properties, and biocompatibility. Such behavior may be attributed to the applied deposition method, resulting in the high hardness of the coating and high adhesion of carbon nanotubes to the substrate. On the other hand, bilayer coating, and hybrid coating demonstrated insufficient properties, which could be the reason for the presence of soft porous hydroxyapatite and some agglomerates of nanometals in prepared coatings.

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Section: Introductionmentioning

confidence: 99%

Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy

et al. 2019

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“…Figure 1. Main nanosystems tested for the treatment of lung cancer Source: Adapted from Cho et al (23) ; Mohanta et al (24) ; Pinho & Figueiras (25) ; Zaborski (26) ; Sharma et al (27) Nanocarriers have the potential to modify the properties of drugs by increasing their efficacy, stability and solubility, as well as reducing their toxicity and sustaining their release (18,22) . The first drug inserted in nanoparticles and approved by the US Food and Drug Administration (FDA) was DOXIL ( Figure 2), which is doxorubicin encapsulated in a lipid nanoparticle.…”

Section: Resultsmentioning

confidence: 99%

Nanoparticles in the Use of Natural Products for the Treatment of Lung Cancer

et al. 2019

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Objetivo: Realizar un estudio bibliográfico sobre el uso de nanopartículas en el transporte de productos naturales para el tratamiento del cáncer de pulmón. Métodos: Se realizó una revisión bibliográfica utilizando los descriptores “Nanoparticles”, “Biological Products” y “Lung Neoplasms”, a través de las bases de datos ScienceDirect, PubMed y SciELO, en el período comprendido entre 2009 y 2018. Resultados: Después del análisis de los artículos de acuerdo con los criterios de inclusión, obtuvimos 31 artículos, de los cuales 25.81% hacían referencia a productos naturales en el tratamiento del cáncer de pulmón, el 29.03% a nanopartículas en el tratamiento del cáncer de pulmón y un 45.16 % a nanopartículas como agentes transportadores de productos naturales para el tratamiento del cáncer de pulmón. Conclusión: El uso de nanopartículas permite el transporte de productos naturales, aumentando sus propiedades terapéuticas contra las células de cáncer de pulmón, además de disminuir los efectos secundarios de estos agentes altamente tóxicos.

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“…Concerning the use of nanomaterials, an in‐depth nanotoxicity assessment needs to be carried out to ensure the safe use for both the manufacturers' operators and the end‐users. Some studies have already been reported, [ 97,267–271 ] but further understanding of all the possible toxicity aspects and long‐term effects is needed.…”

Section: Prospects Future Challenges and Conclusive Remarksmentioning

confidence: 99%

Transparent Heaters: A Review

Papanastasiou

Schultheiss

Muñoz‐Rojas

et al. 2020

Adv Funct Materials

187

191

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Transparent heaters (TH) have attracted intense attention from both scientific and industrial sectors due to the key role they play in many technologies, including smart windows, deicers, defoggers, displays, actuators, and sensors. While transparent conductive oxides have dominated the field for the past five decades, a new generation of THs based on nanomaterials has led to new paradigms in terms of applications and prospects in the past years. Here, the most recent developments and strategies to improve the properties, stability, and integration of these new THs are reviewed.

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Carbon nanotubes: Evaluation of toxicity at biointerfaces

Cited by 227 publications

References 68 publications

Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy

Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy

Nanoparticles in the Use of Natural Products for the Treatment of Lung Cancer

Transparent Heaters: A Review

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