Carbon nanotube–ruthenium hybrid towards mild oxidation of sulfides to sulfones: efficient synthesis of diverse sulfonyl compounds

Abstract

Ru nanoparticles on carbon nanotubes were used in the mild oxidation of sulfides to sulfones.

Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2

“…Compounds containing sulfur, as sulfoxides and sulfones [98,99], selenium [100], iodine [47], amines, bromine, hydroxyls, alkenes, among other substituent groups [46,[101][102][103][104][105][106][107] were studied and evaluated according to their potential to act as anti-SARS-CoV-2. Imine derivatives were also targeted in our studies and were placed in group 6 [67].…”

“…were prepared as described in the literature [90]. Para-quinones and derivatives 379, 380, 382, 414, 415, 465, 470, 477, were synthesized following the previously published studies in the literature [76,99]. Hydrazo derivatives 666, 668 and 673 were prepared according to previously published reports and their data are consistent with the literature [68].…”

Synthesis and Applications of Periodate for Fine Chemicals and Important Pharmaceuticals

“…A ruthenium/periodatecatalyzed sulfide oxidation was demonstrated to work with immobilized ruthenium on carbon nanorods. 493 Finally, we want to focus on biologically active Ncyanosulfoximines, which represent a hot topic currently. 494−497 Very recently, an electrochemical method was developed by our group and the efficient synthesis of sulfoxaflor (Isoclast), a commercial insecticide, was showcased (Scheme 59).…”

“…Related important compounds are sultamicillin ( Unacid , Pfizer ) and sulbactam. A ruthenium/periodate-catalyzed sulfide oxidation was demonstrated to work with immobilized ruthenium on carbon nanorods …”

Pyridylidene Amide Ru Complex for Selective Oxidation in Organic Synthesis

“…Likewise, they are key functional entities in herbicides, e.g., in Mesotrione or Cafenstrole . A general challenge in the preparation of sulfones from sulfides is often the incomplete oxidation. , Full oxidation has been achieved with carbon nanotubes-Ru and NaIO 4 and with different high-valent molybdenum systems and organocatalyzed with the use of ozone . While ozone is inconvenient as the terminal oxidant due to its hazardous properties, NaIO 4 constitutes a suitable alternative that is also potentially applicable for large scale preparations …”