Carbon Nanotube Electrodes in Comparison to Coated Platinum Wire and Carbon Paste Selective Electrodes for the Determination of Tramadol Hydrochloride in Bulk, Pharmaceutical Formulations, and Spiked Human Plasma and Urine
Abstract:Potentiometric selective electrodes are designed for the electrochemical determination of tramadol hydrochloride (TR.HCl). They are synthesized using coated platinum wire, a carbon paste electrode, and multiwall-carbon-nanotube (MWCNT)-modified carbon paste electrodes. The membranes of the studied electrodes use different types of ionophores as a key element in TR.HCl detection, such as 18-crown-6-ether, β cyclodextrin, and calix[4]arene neutral ionophores. The matrix composition of each electrode is optimized… Show more
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