Carbon nanostructures: a comprehensive review of potential applications and toxic effects

Farmand, Maryam; Jahanpeyma, Fatemeh; Gholaminejad, Alieh; Azimzadeh, Mostafa; Malaei, Fatemeh; Shoaie, Nahid

doi:10.1007/s13205-022-03175-6

Cited by 14 publications

(7 citation statements)

References 323 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CNSs can be internalized by cells, potentially leading to cytotoxic effects such as oxidative stress, inflammation, and cell death. The unique shape and size of CNSs may cause physical interference with cellular components and biological processes (Farmand et al, 2022).…”

Section: Toxicity and Biodegradabilitymentioning

confidence: 99%

Carbon Nanostructures as promising Targeted Drug Delivery systems of Anticancer Agents

Elsayed

2024

International Journal of Cancer and Biomedical Research

View full text Add to dashboard Cite

Nanotechnology has opened new paths for cancer treatment, with carbon nanostructures (CNSs) becoming drug delivery vehicles. This review examines fullerenes, carbon nanotubes (CNTs), graphene, and their derivatives as effective drug delivery vehicles for anticancer therapies. Their high surface area, ease of functionalization, exceptional thermal and electrical conductivity, and ability to cross biological barriers make them ideal candidates for improving anticancer drug specificity, bioavailability, and therapeutic efficacy while minimizing systemic toxicity. The biocompatibility and changeable surfaces of CNSs provide targeted delivery to treat cancer cell heterogeneity. This precision targeting reduces chemotherapy side effects. Adding ligands, antibodies, and peptides to CNSs makes them more selective for cancer cells, letting the therapeutic payload go to the tumor site. Because they absorb a lot of light, graphene-based nanostructures can be used in photothermal therapy and photoacoustic imaging to treat and keep an eye on cancers without cutting them open. CNSs in multimodal cancer treatment techniques, such as radiochemotherapy, may improve cancer treatment. After clinical research and biocompatibility improvements, CNSs could transform cancer treatment with more precise, efficient, and less toxic choices. Thus, using carbon nanostructures in cancer treatment marks a breakthrough in nanomedicine and a new age of focused and effective cancer treatments.

show abstract

Section: Toxicity and Biodegradabilitymentioning

confidence: 99%

Carbon Nanostructures as promising Targeted Drug Delivery systems of Anticancer Agents

Elsayed

2024

International Journal of Cancer and Biomedical Research

View full text Add to dashboard Cite

show abstract

“…Metal-based NPs (gold, silver, iron), oxides (iron oxide), semiconductor structures (quantum dots), carbon dots and nanotubes are among the best studied [ 34 ], though there are many sizes, shapes, and structures available. There are data connecting at least some inorganic NPs to undesirable biological reactions, such as promoting inflammation, fibrosis, or tumorigenesis (the link between lung cancer and carbon nanostructure exposure is documented) [ 35 , 36 ].…”

Section: Nanoparticlesmentioning

confidence: 99%

The Usefulness of Nanotechnology in Improving the Prognosis of Lung Cancer

et al. 2023

View full text Add to dashboard Cite

Lung cancer remains a major public health problem both in terms of incidence and specific mortality despite recent developments in terms of prevention, such as smoking reduction policies and clinical management advances. Better lung cancer prognosis could be achieved by early and accurate diagnosis and improved therapeutic interventions. Nanotechnology is a dynamic and fast-developing field; various medical applications have been developed and deployed, and more exist as proofs of concepts or experimental models. We aim to summarize current knowledge relevant to the use of nanotechnology in lung cancer management. Starting from the chemical structure-based classification of nanoparticles, we identify and review various practical implementations roughly organized as diagnostic or therapeutic in scope, ranging from innovative contrast agents to targeted drug carriers. Available data are presented starting with standards of practice and moving to highly experimental methods and proofs of concept; particularities, advantages, limits and future directions are explored, focusing on the potential impact on lung cancer clinical prognosis.

show abstract

“…These bonds are highly reactive sites found in high densities on carbon black and least in CNTs. On the other hand, Isobe et al [133] estimated the cytotoxic potential of the CNTs and found them to have only low levels of toxicity [134].…”

Section: Carbon Nanotubes (Cnt)mentioning

confidence: 99%

Prospects of nanosorption and photocatalysis in remediation of oil spills

Shaibu

Inam

Moses

et al. 2023

J. Nig. Soc. Phys. Sci.

View full text Add to dashboard Cite

Nanoremediation approaches have been applied to remove oil from surface and ground water as oil spills have been found to have long-term negative consequences for the ecosystem. Nanoremediation via the nanosorption mechanism of different environmental matrices in the world at large is at its formative stages despite the alarming and extensive prevalence of petroleum related environmental pollution. Over 9 million barrels of oil have been leaked in the last five decades, making that ecosystem one of the most deteriorated by oil exploration and extraction activities. The goal of this research is to assess the current status, trends, and future prospects of the nanosorption of surface and ground water in oil spill regions. High surface area of nanomaterials, wide spectrum of treatable contaminants, non-generation of intermediate or secondary products, as well as speed and extent of contaminant destruction give nanoremediation a superior comparative edge over other treatment technologies. Notably, the remediation efficiency of a cleanup is highly dependent on the type of material and treatment routes employed. It is imperative to employ a concerted and practical approach to the development of nanotechnology to combat the bedeviling oil pollution challenges faced in oil producing counties.

show abstract

Carbon nanostructures: a comprehensive review of potential applications and toxic effects

Cited by 14 publications

References 323 publications

Carbon Nanostructures as promising Targeted Drug Delivery systems of Anticancer Agents

Carbon Nanostructures as promising Targeted Drug Delivery systems of Anticancer Agents

The Usefulness of Nanotechnology in Improving the Prognosis of Lung Cancer

Prospects of nanosorption and photocatalysis in remediation of oil spills

Contact Info

Product

Resources

About