Encyclopedia of Forensic and Legal Medicine 2016
DOI: 10.1016/b978-0-12-800034-2.00057-4
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Carbon Monoxide Exposure: Clinical Findings – Sequelae in Survivors

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“…Since the relative affinity of CO for Hb is higher by 200 to 250 times than that of Oxygen, it can easily displace Oxygen in the blood to form Carboxyhemoglobin (COHb), (Stork, 2014;Payne-James, 2016). Consequently, this ends up in hypoxemia, tissue hypoxia and when the COHb is circulated within the body it causes Asphyxia.…”
Section: Epidemiology Of Oxides Of Carbon Inhalationmentioning
confidence: 99%
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“…Since the relative affinity of CO for Hb is higher by 200 to 250 times than that of Oxygen, it can easily displace Oxygen in the blood to form Carboxyhemoglobin (COHb), (Stork, 2014;Payne-James, 2016). Consequently, this ends up in hypoxemia, tissue hypoxia and when the COHb is circulated within the body it causes Asphyxia.…”
Section: Epidemiology Of Oxides Of Carbon Inhalationmentioning
confidence: 99%
“…Consequently, this ends up in hypoxemia, tissue hypoxia and when the COHb is circulated within the body it causes Asphyxia. CO poisoning targets mostly organs with high oxygen demand such as the heart and central nervous system leading to dizziness, loss of coordination and headache as well as delayed neuropsychiatric sequelae (Stork, 2014;Payne-James, 2016;Lee and Bye, 2019;Betterman and Patel, 2014). Since CO health problems are dose dependent, the inhalation at low concentrations can cause fatigue even in healthy people while at higher quantities it can lead to reduce blood supply to the heart (myocardial Ischemia), irregular rhythm of the heart (cardiac dysrhythmia), lethargy (physical and mental dullness) due to carbon monoxide induced fatigue (Stork, 2014;Payne-James, 2016;Lee and Bye, 2019;Betterman and Patel, 2014).…”
Section: Epidemiology Of Oxides Of Carbon Inhalationmentioning
confidence: 99%
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