Carbon dots as potential antioxidants for the scavenging of multi-reactive oxygen and nitrogen species

Dual enzyme-mimicking carbon dots for enhanced antibacterial activity

“…S5, ESI†), because of the electron excitation caused by the π–π* transition and is consistent with the UV-vis spectroscopy results. 41 Interestingly, Co doping caused the quantum yield of the Co-Lvx-CDs (21.8%) to decrease slightly relative to the Lvx-CDs (30.08%) (Fig. S6 and S7, ESI†).…”

Ultrahigh‐Efficacy VEGF Neutralization Using Carbonized Nanodonuts: Implications for Intraocular Anti‐Angiogenic Therapy

“…We speculate that the transfer of hydrogen atoms from the phenolic functional groups of the CNDs to the DPPH⋅ radicals followed by the resonance delocalization with the nitrogen atoms in the aromatic moieties leads to fast electron transfer, thereby resulting in higher antioxidant activity. [ 32 ] Therefore, we further employed 2′,7′‐dichlorofluorescein diacetate (DCFH‐DA) assay with H 2 O 2 (250 µM)‐induced oxidative stress in human retinal pigment epithelial (ARPE‐19) cells, showing mild antioxidant activities of SA and SA‐CNPs (Figure 3B), [ 45,46 ] whereas all the three SA/DAO‐CNDs exhibit higher antioxidant activities as evident from the negligible fluorescence. The enhanced antioxidant activity of SA/DAO‐CNDs compared with SA‐CNPs indicates that DAO plays a significant role, mainly through the formation of heteroatom‐containing graphitic structures in the CNDs which facilitate electron and proton transfers.…”

Synthetic strategies, properties and sensing application of multicolor carbon dots: recent advances and future challenges

“…Since then, developing fascinating CDs with versatile properties has received great attention in many fields. [7][8][9][10][11] The most predominant characteristic of CDs is that they have remarkable properties, such as tunable photoluminescence, 12 high fluorescence quantum yield (QY), 13,14 ease of surface functionalization, 15 good aqueous solubility, 16 superior biocompatibility, 17 and high photostability, 18,19 have received immense research attention, which enables CDs to be an excellent alternative to semiconductor quantum dots (QD) with a wide variety of promising applications in the fields of sensing, 20 bioimaging, 21 biomedicine, 22 electronic devices, 23 and anti-counterfeiting. 24 In the initial development stage of CDs, the main research focuses on the preparation of carbon dots, utilizing a large number of carbon sources and numerous approaches.…”

“…In addition, they explored the chemical composition and luminescence mechanism of polychromatic CDs, which sparked research interest in the luminescence mechanism and application of polychromatic CDs. The “bottom-up” approach synthesizes CDs using carbon-bearing molecules through a carbonization and dehydration process, which can be achieved by means of hydrothermal/solvothermal, 7,30 and microwave-assisted pyrolysis. 31,32 Zhu et al 33 prepared multicolor CDs using a microwave pyrolysis method for carbonization of poly(ethylene glycol) (PEG) and saccharide, showing excitation-dependence with QYs of 6.3–3.1%.…”