Carbon ceramic electrode incorporated with zeolite ZSM-5 for determination of Piroxicam

Abstract

Abstract:A new chemically modified electrode is constructed based on carbon ceramic electrode incorporated with zeolite ZSM-5. Voltammetric behavior of piroxicam at the carbon ceramic zeolite modified electrode (CCZME) was investigated. The modified electrode exhibited catalytic activity toward the electrooxidation of piroxicam. Experimental parameters such as solution pH, scan rate, concentration of piroxicam and zeolite amount were studied. It has been shown that using the CCZME, piroxicam can be determined by differential pulse voltammetry (DPV) and hydrodynamic amperometry (HA). Under the optimized conditions the calibration plots are linear in the concentration ranges of 0.20-25.00 and 0.20-50.10 μM with limit of detections of 0.65 and 0.29 μM for DPV and HA, respectively. The modified electrode with DPV and HA methods was successfully applied for analysis of piroxicam in pharmaceutical formulations. The results were favorably compared to those obtained by the spiked method. The results of the analysis suggest that the proposed method has promise for the routine determination of piroxicam in the products examined.

Simple and Fast Determination of Piroxicam in Pharmaceutical and Real Samples Using Glassy Carbon Electrode Modified with Copper Nano-particles

“…Piroxicam molecule contains functional groups which are more interesting in view of electrochemical study and the electro-oxidation of piroxicam has been investigated by various studies. [11][12][13][39][40][41][42][43][44][45] The electrochemical oxidation of piroxicam shows an anodic peak at the positive moving step without any cathodic peak on the reverse scan, which indicated that the oxidation reaction is irreversible. Hence, the anodic peak current was used for determination of piroxicam.…”

Fabrication and Application of Ferrierite–Modified Carbon Ceramic Electrode in Sensitive Determination of Estradiol

“…19 K. Asadpour-Zeynali and co-workers proposed also carbon ceramic electrode modified using zeolite-ZSM-5. 20 In all cases the positive influence of zeolite on z E-mail: justynarobak@poczta.fm electrode sensitivity was confirmed. Nevertheless, so far ferrieritemodified carbon ceramic electrodes have not been investigated.…”