Carbon as an implant material in orthopaedic surgery

Rettig, H; Weber, U.; Brückmann, H.; Rosenblatt, U.; Kj, Hüttinger

doi:10.1007/bf00383407

Cited by 5 publications

(3 citation statements)

References 5 publications

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“…PyC has been investigated for use in hip replacements since the 1980s (98), but only a few papers deal with the results obtained by in vivo tests in the clinical setting. Rettig et al (99) made mention of experimental PyC hip replacements in beagles without reporting the outcomes of these experimental implants. Jung et al (100) evaluated hemiprostheses made of PyC-coated graphite in rabbits, observing degenerative damage of the cartilage 12 weeks postoperatively in histologic sections.…”

Section: Pyrolytic Carbon Coatingsmentioning

confidence: 99%

Clinical Outcomes of Ceramicized Ball Heads in Total Hip Replacement Bearings: A Literature Review

Piconi

Santis

Maccauro

2017

Journal of Applied Biomaterials & Functional Materials

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Section: Pyrolytic Carbon Coatingsmentioning

confidence: 99%

Clinical Outcomes of Ceramicized Ball Heads in Total Hip Replacement Bearings: A Literature Review

Piconi

Santis

Maccauro

2017

Journal of Applied Biomaterials & Functional Materials

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“…Nowadays it is an industry standard due to its advantageous properties: it is biocompatible (does not trigger adverse reactions when implanted in the human body), it is thromboresistant (prevents blood clotting) and provides good durability, wear resistance and strength. For these reasons, pyrolytic carbon is currently used in prosthetic heart valves and orthopedic joints [6]. To date, millions of devices have already been implanted.…”

Section: Introductionmentioning

confidence: 99%

Carbon microelectromechanical systems as a substratum for cell growth

et al. 2008

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The study of the biocompatible properties of carbon microelectromechanical systems (carbon-MEMS) shows that this new microfabrication technique is a promising approach to create novel platforms for the study of cell physiology. Four different types of substrates were tested, namely, carbon-MEMS on silicon and quartz wafers, indium tin oxide (ITO) coated glass and oxygen-plasma-treated carbon thin films. Two cell lines, murine dermal fibroblasts and neuroblastoma spinal cord hybrid cells (NSC-34) were plated onto the substrates. Both cell lines showed preferential adhesion to the selectively plasma-treated regions in carbon films. Atomic force microscopy and Fourier transform infrared spectroscopy analyses demonstrated that the oxygen-plasma treatment modifies the physical and chemical properties of carbon, thereby enhancing the adsorption of extracellular matrix-forming proteins on its surface. This accounts for the differential adhesion of cells on the plasma-treated areas. As compared to the methods reported to date, this technique achieves alignment of the cells on the carbon electrodes without relying on direct patterning of surface molecules. The results will be used in the future design of novel biochemical sensors, drug screening systems and basic cell physiology research devices.

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“…Its immense popularity as a biomaterial stems from multiple advantages such as biocompatibility, thromboresistance, durability, mechanical strength, and electrical conductivity [16], [18]. The usage of carbon includes substrates and scaffolds, electrochemical biosensors, and electrophysiological devices [19]- [24].…”

mentioning

confidence: 99%

Immersion Lithographic Patterning of Electrospun Nanofibers for Carbon Nanofibrous Microelectrode Arrays

Jao

Franca

Fang

et al. 2015

J. Microelectromech. Syst.

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Immersion photolithography of electrospun SU-8 nanofibers followed by carbonization has been demonstrated for 3-D carbon nanofibrous microelectrodes. The process and resultant structures offer unique advantages: 1) precise patterning of nanofibrous microstructures via refractive index matching immersion photolithography; 2) good cell/neuron adhesion characteristic of the resultant scaffold attributed to nanomorphology in 100's nanometer scale; 3) high electrical conductivity of the carbonous microelectrodes appropriate for neural stimulation and signal detection; and 4) biocompatibility of the carbon nanofibers. Immiscible refractive index matching liquid, such as oil (n oil = 1.47), has been applied to the nonhomogeneous nanofiber stack consisting of SU-8 nanofibers (n SU−8 = 1.67) and air (n air = 1) before ultraviolet light exposure, which greatly suppresses optical diffraction and scattering effects, resulting in high aspect ratio 3-D nanofibrous microstructures and enhanced patterning resolution. The aspect ratio of the fabricated 3-D structures is increased from 0.26 to 0.89 and the contrast ratio from 0.56 to 0.96, compared with ones from the nonimmersion process. Ray tracing simulation taking into account diffraction effects in nanofibrous media has been discussed. Microelectrode arrays consisting of integrated nanofibers and thin-film carbon structures are implemented for in vitro neuron culture experiments. Experimental results of structure's surface roughness, electrical conductivity, and cell viability on them are detailed.[ 2014-0160]Index Terms-Nanofibrous 3-D microstructure, nanofiber lithography, Huygen-Fresnel, nanofiber diffraction, immersion lithography, nanofibrous microelectrode array, carbon nanofibers.

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Carbon as an implant material in orthopaedic surgery

Cited by 5 publications

References 5 publications

Clinical Outcomes of Ceramicized Ball Heads in Total Hip Replacement Bearings: A Literature Review

Clinical Outcomes of Ceramicized Ball Heads in Total Hip Replacement Bearings: A Literature Review

Carbon microelectromechanical systems as a substratum for cell growth

Immersion Lithographic Patterning of Electrospun Nanofibers for Carbon Nanofibrous Microelectrode Arrays

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