“…Traditionally, the plant is used as a stimulant, stomachic, febrifuge, analgesic and for the treatment of diarrhoea, dysentery and insect bites (Kirtikar et al, 1993;Yusuf et al, 1994). Previous phytochemical investigations on this plant revealed the occurrence of carbazole alkaloids (Narasimhan et al, 1968;Chowdhury and Chakraborty, 1971;Chakraborty et al, 1978;Rao et al, 1980;Bhattacharyya et al, 1982;Roy et al, 1982;Fiebig et al, 1985;Bhattacharyya and Chowdhury, 1985;Ito et al, 1993;Reisch et al, 1994;Saha and Chowdhury, 1998;Nutan et al, 1999;Ramsewak et al, 1999;Tachibana et al, 2001;Knolker and Reddy, 2002) and coumarins (Adebajo and Reisch, 2000;Murray et al, 1982). As a part of our research project focussing on Bangladeshi rutaceous species, we here report the isolation of a new benzoisofuranone derivative (10) and a new dimeric carbazole alkaloid (11) together with six known carbazoles and three known steroids from the stem bark of M. koenigii as well as the antimicrobial activities of compounds 1-3 and 6-11.…”