Carbazole alkaloids from Murraya koenigii

Nootropic Potential of Murraya koenigii leaves in Rats

“…Antioxidant carbazoles have been reported present in MKL may be favorably contributing to the memory enhancing effect seen in the present study. Thus, the protective effect of MKL may be attributed to its antioxidant property by virtue of which susceptible brain cells get exposed to less oxidative stress resulting in reduced brain damage and improved neuronal function (Chakrabarty et al, 1997;Ramsewak et al, 1999;Tachibana et al, 2001;Wang et al, 2003).…”

“…Ayurvedic literature as well as recent studies highlights the potential of MKL as an antidiabetic agent (Yadav et al, 2002;Adebajo et al, 2004Adebajo et al, , 2006Kesari et al, 2005). Leaf extract of Murraya koenigii have also been reported to posses antifungal, antineoplastic, nitric oxide scavenging and antioxidant activities (Das et al, 1965;Khan et al, 1996a;Chakrabarty et al, 1997;Khan et al, 1997;Ramsewak, et al, 1999;Tachibana et al, 2001;Baliga et al, 2003). Anti-oxidant, Antitumor, Anti-microbial and Anti-diabetic actives have been reported for some carbazole alkaloids, which were identified as the major compounds in Murraya koenigii leaves (Tachibana et al, 2001;Adebajo et al, 2004Adebajo et al, , 2006Ito et al, 2006).…”

Murraya koenigii

“…It is traditionally used as a whole or in parts as antiemetics, antidiarrheal, febrifuge, blood purifier, antifungal, depressant, anti-inflammatory, body aches, for kidney pain and vomiting. [24][25][26][27][28][29][30][31][32] .…”

Synthesis and Cytotoxic Activity Evaluation of Novel Derivatives of Murrayafoline A

“…A number of natural carbazole alkaloids were recognized to exhibit potential biological activities such as antimicrobial [1,2], anti-HIV [3], anticancer [4,5,6] activities. Among them, several compounds were used as drugs for treatment of cancer [7].…”